Objective: To analyze the factors associated with negative health perception in older Brazilians.
Methods: Population study of a cross-sectional sample, conducted in 2009 in three cities of Brazil. The stratified simple random sample consisted of 909 adults between 60 and 91 years of age. A gross and multivariate analysis by estimated prevalence rate (PR) using Poisson regression with calculation of adjusted prevalence ratios, p < 0.05 was performed to identify factors associated with negative perception of health (NPH).
Results: The prevalence of NPH was 49.6%. After the multivariate association, a certain association for men with older age PR = 1.03 (Cl = 1.01 to 1.06), risk of malnutrition PR = 1.66 (CI = 1.13 to 2.43) and disability PR = 1.79 (CI = 1.21 to 1.77) was observed. For women, the association was with taking more than two medications PR = 1.41 (CI = 1.13 to 2.52), hypertension PR = 1.52 (CI = 1.43 to 1.97) and functional disability PR = 1.36 (CI = 1.13 to 1.86).
Conclusions: Nearly half of the elderly have NHP, therefore preventive actions that decrease drug use and encourage behaviors toward better nutritional conditions should be tied to public policies in order to promote the functional independence and well-being of the elderly.
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http://dx.doi.org/10.1590/s1415-790x2012000100005 | DOI Listing |
Endocrinol Diabetes Metab
January 2025
Department of Endocrinology and Metabolism, Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Objective: This study investigates the relationship between the albumin-to-creatinine ratio and diabetic retinopathy (DR) in US adults using NHANES data from 2009 to 2016. This study assesses the predictive efficacy of the urinary serum albumin-to-creatinine ratio (UACR/SACR Ratio) against traditional biomarkers such as the serum albumin-to-creatinine ratio (SACR) and urinary albumin-to-creatinine ratio (UACR) for evaluating DR risk. Additionally, the study explores the potential of these biomarkers, both individually and in combination with HbA1c, for early detection and risk stratification of DR.
View Article and Find Full Text PDFGut Microbes
December 2025
Department of Pediatrics, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Ministry of Education), West China Second University Hospital, Sichuan University, Chengdu, China.
Necrotizing Enterocolitis (NEC) is a severe, life-threatening inflammatory condition of the gastrointestinal tract, especially affecting preterm infants. This review consolidates evidence from various biomedical disciplines to elucidate the complex pathogenesis of NEC, integrating insights from clinical, microbial, and molecular perspectives. It emphasizes the modulation of NEC-associated inflammatory pathways by probiotics and novel biologics, highlighting their therapeutic potential.
View Article and Find Full Text PDFJ Crohns Colitis
January 2025
Servei d'Aparell Digestiu, Hospital Universitari Germans Trias i Pujol (Badalona, Catalonia, Spain).
Background And Aims: Inflammatory bowel disease (IBD) develops in genetically susceptible individuals exposed to certain environmental factors, of which only a few have been established. We aimed to assess whether bariatric surgery (BS) and severe obesity are associated with an increased risk of developing IBD.
Methods: Adults diagnosed with obesity or severe obesity between 2005 and 2020 were identified from the Catalan Health Surveillance System; those diagnosed with IBD prior to the diagnosis of obesity or severe obesity were excluded.
Paediatr Drugs
January 2025
Institute of Clinical Pharmacology, Peking University First Hospital, Beijing, China.
Background: This study aimed to provide a comprehensive review of adverse events (AEs) associated with factor Xa (FXa) inhibitors in pediatric patients.
Methods: We searched PubMed, Embase, Cochrane Library, ClinicalTrials.gov, and the European Union Clinical Trials Register for English-language records from the establishment of the database up to October 17, 2023.
Jpn J Ophthalmol
January 2025
Department of Visual Science and Ophthalmology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Purpose: To review hospitalized patients with Acute Retinal Necrosis (ARN) and investigate factors associated with subsequent retinal detachment (RD).
Study Design: Retrospective.
Methods: The study included 40 patients (42 eyes), categorized into non-RD (23 eyes) and RD (19 eyes) groups.
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