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Evaluation and differential diagnosis of marked, persistent eosinophilia. | LitMetric

Evaluation and differential diagnosis of marked, persistent eosinophilia.

Semin Hematol

Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892-0425, USA.

Published: April 2012

High-grade eosinophilia can be a diagnostic dilemma, as the etiologies are extensive and varied. Hypereosinophilic syndromes (HES) are a group of heterogeneous disorders, many of which remain poorly defined. By definition, HES must be distinguished from other disorders with persistently elevated eosinophilia with a defined cause. Although marked eosinophilia worldwide is most commonly caused by helminth (worm) infections, non-infectious causes must be considered, and include drug reactions, malignancies, and immunologic, inflammatory and allergic diseases.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3314223PMC
http://dx.doi.org/10.1053/j.seminhematol.2012.01.006DOI Listing

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