The results of the treatment of 38 children (6 boys and 32 girls, age 6-14 years) with chronic pyelonephritis and/or cystitis complicated with neurogenic dysfunction of the urinary bladder (NDUB) and/or vesicoureteral reflux (VUR) of the first-third degree demonstrate efficacy of intravesical electrostimulation (IVES) and adrenal magnetotherapy. IVES was conducted with high-frequency current impulses (2.2 kHz) by means of INTRASTIM attachment to the device AMUS-01-INTRAMAG in the region of the urethrovesical anastomosis via solution of the drugs for instillation. As the result of exposure to both physical factors in the presence of standard medication, NDUB symptoms alleviated (by E.L. Vishnevsky's criteria) by 59.5% against 38.1% in the control group. Dopplerographic examination of renal vessels stated a 24.3% increase in blood flow in the major renal artery in the study group against 10.5% in the control. The proposed complex pharmacological plus physiotherapeutic treatment of chronic pyelonephritis and cystitis in abnormal urodynamics resulted in a 2.2-fold decrease in the number of recurrences compared to the standard treatment.
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Cureus
November 2024
Nephrology, Stanley Medical College, Chennai, IND.
Background Diabetes mellitus (DM) is a prevalent predisposing factor for urinary tract infections (UTIs). Among hospitalized patients with acute pyelonephritis, UTIs are more common, severe, and associated with worse outcomes, particularly in those with type 2 DM. Pyelonephritis in DM patients is more frequently bilateral and linked to greater complications, with 90% of emphysematous pyelonephritis (EMPN) and cystitis cases occurring in diabetic individuals.
View Article and Find Full Text PDFFront Pharmacol
December 2024
Department of Infectious Disease, Shaoyang Central Hospital, Shaoyang, China.
Objective: To investigate which fluoroquinolone is safer when combined with bedaquiline for tuberculosis treatment by using the FDA Adverse Event Reporting System (FAERS) database.
Methods: We selected data from the first quarter (Q1) of 2013 to the second quarter (Q4) of 2024 from the FDA FAERS database for disproportionality analysis. Signal detection was conducted using the Reporting Odds Ratio (ROR), Proportional Reporting Ratio (PRR), Bayesian Confidence Propagation Neural Network (BCPNN), and Empirical Bayesian Geometric Mean (EBGM).
Cureus
November 2024
Emergency Medicine, St. Mary's Hospital, Isle of Wight NHS Trust, Isle of Wight, GBR.
Renal infarction is a rare but potentially serious condition, often misdiagnosed due to its non-specific presentation, which mimics conditions such as nephrolithiasis and pyelonephritis. Discussed in this case report is a 68-year-old woman who presented to an emergency department with two weeks of worsening left flank pain. She was found to have a new diagnosis of atrial fibrillation (AF) on electrocardiogram (ECG) and CT findings revealing renal infarction.
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October 2024
Community Medicine Management, Shimane University Faculty of Medicine, Izumo, JPN.
Introduction Hypoglycemia is a significant clinical concern among hospitalized elderly patients, particularly those with acute illnesses such as pyelonephritis. It is associated with increased morbidity and mortality. Identifying specific risk factors for hypoglycemia in this vulnerable population is crucial to developing targeted interventions and improving patient outcomes.
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