Animals were immunized with transmissible gastroenteritis virus conjugated with gold nanoparticles. The resultant antibodies had a higher titer than antibodies produced in response to native virus. Immunization with the antigen-colloidal gold complex led to a significant increase of the peritoneal macrophages respiratory activity and of plasma IFN-γ level in immunized animals.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087599PMC
http://dx.doi.org/10.1007/s10517-011-1350-8DOI Listing

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