[Effect of sucrose on lipid metabolism in rats: confirmation of the disaccharide effect].

Disaccharide effect of sucrose on lipid metabolism was confirmed in male Wistar rats (initial weight 119-127 g). The rats were given rations containing either sucrose (30% of total caloric++ value), or invert sugar, or starch only (control). The duration of the dietary period was 40 days. To study lipid metabolism the rats were injected i. p. with 1-14C-glucose and 3H-palmitic acid. 14C-radioactivity increased in the total lipid of serum and epididymal adipose tissue, in liver phospholipids and mostly in liver neutral lipids with the saccharose-supplemented diet but not with invert sugar-supplemented diet. In contrast, 3H-radioactivity in liver phospholipids decreased in rats that were given saccharose, no changes were recorded in the animals fed with invert sugar or starch.