Objective: The Conners Adult ADHD Rating Scales (CAARS) assess symptoms specific to adults that are frequently used and have been translated into German. The current study tests the factor structure of the CAARS in a large sample of German adults with ADHD and compares the means of the CAARS subscales with those of healthy German controls.
Method: CAARS were completed by 466 participants with ADHD and 851 healthy control participants. Confirmatory factor analysis was used to establish model fit with the American original. Comparisons between participants with ADHD and healthy controls and influences of gender, age, and degree of education were analyzed.
Results: Confirmatory factor analysis showed a very good fit with the model for the American original. Differences between ADHD participants and healthy controls on all Conners Adult ADHD Rating Scales-Self-Report (CAARS-S) subscales were substantial and significant.
Conclusion: The factor structure of the original American model was successfully replicated in this sample of adult German ADHD participants.
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http://dx.doi.org/10.1177/1087054711435680 | DOI Listing |
Musculoskeletal Care
March 2025
Clinical Trials Research Unit, University of Leeds, Leeds, UK.
Introduction: Persistent knee pain often due to knee osteoarthritis (OA) is a highly prevalent and disabling condition. Electronic-rehabilitation (e-rehab) programmes have the potential to support self-management of knee OA. This study aimed to evaluate user engagement and acceptability of two e-rehab programmes, Group e-rehab, a remote physiotherapy-led programme and My Knee UK, a self-directed web-based exercise programme.
View Article and Find Full Text PDFJ Virol
December 2024
Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Enteric pathogen rotavirus (RV) primarily infects mature enterocytes at the tips of the intestinal villi; however, the role of secretory Paneth and goblet cells in RV pathogenesis remains unappreciated. Atoh1 knockout mice (Atoh1cKO) were used to conditionally delete Paneth, goblet, and enteroendocrine cells in the epithelium to investigate the role of secretory cells in RV infection. Unexpectedly, the number of infected enterocytes and the amount of RV shedding in the stool were greatly decreased following secretory cell deletion.
View Article and Find Full Text PDFCurr Dev Nutr
January 2025
Discipline of Nutrition, School of Medical Sciences, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.
Background: A healthy diet has been proposed to support good mental health, but the addition of either red meat or meat alternatives is nuanced.
Objectives: We aimed to determine if psychological and physiological well-being is differentially affected by consuming recommended weekly amounts of either lean red meat or plant-based meat alternatives (PBMAs) supplemented with a plant-rich diet.
Methods: The trial was a parallel 2-arm randomized intervention of 10 wk duration.
Appl Psychol Health Well Being
February 2025
University of Bremen, Bremen, Germany.
Behavioral intentions predict behavior better if they are stable over time. A statistical argument suggests that this is due to less measurement error, but recent theoretical advances suggest self-regulatory effects: durable intentions remain temporally stable due to their persistence when faced with challenges. Here, we leverage intensive longitudinal data on adherence with non-pharmaceutical interventions (NPIs) during the COVID-19 pandemic (N = 623; total assessments = 19,740; study duration: 6 months each).
View Article and Find Full Text PDFThe corticospinal tract (CST) facilitates skilled, precise movements, which necessitates that subcerebral projection neurons (SCPN) establish segmentally specific connectivity with brainstem and spinal circuits. Developmental molecular delineation enables prospective identification of corticospinal neurons (CSN) projecting to thoraco-lumbar spinal segments; however, it remains unclear whether other SCPN subpopulations in developing sensorimotor cortex can be prospectively identified in this manner. Such molecular tools could enable investigations of SCPN circuitry with precision and specificity.
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