AI Article Synopsis
- The N-tosylcarboxamide group can guide Pd-catalyzed C-H arylation reactions, allowing for the creation of biarylcarboxamide compounds.
- It can adapt to various reaction conditions, including intramolecular reactions, enhancing its versatility in chemical synthesis.
- This functionality is crucial for developing a diverse range of biaryl-based compounds, making it an important tool in organic chemistry.
Article Abstract
The N-tosylcarboxamide group offers the possibility of directing the Pd-catalyzed C-H arylation of arenes providing a new entry to biarylcarboxamides. Moreover, its ability to react according to different reaction conditions including intramolecular reactions makes it a pivotal directing group for a divergent synthesis of biaryl-based compounds.
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| http://dx.doi.org/10.1021/ol3004244 | DOI Listing |
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