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Erlotinib-induced Perioral Lesions Resembling Scleroderma.
Acta Dermatovenerol Croat
November 2024
Constantin A. Dasanu MD, PhD, Lucy Curci Cancer Center, Eisenhower Health, 39000 Bob Hope Dr, Rancho Mirage, CA 92270 , USA;
Erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), is currently used in the therapy of several solid malignancies. This agent has been associated with several dermatological side-effects, the most common being papulo-pustular acneiform rash. Herein we describe a unique skin effect in a patient treated with erlotinib for non-small cell lung cancer.
View Article and Find Full Text PDFA Large Basal Cell Carcinoma Treated With Hedgehog Inhibitor: A Case Report.
Cureus
November 2024
Dermatology, Dermatology Associates of Uptown, Cedar Hill, USA.
Basal cell carcinoma (BCC) is the most commonly diagnosed cutaneous cancer globally. Chronic exposure to environmental triggers and genetic predisposition are risk factors that contribute to the incidence of BCC. While most cases of BCC are treated surgically with curettage or simple excision, treatment options for advanced BCC, including metastatic BCC and locally advanced BCC, are limited as some may be considered unresectable.
View Article and Find Full Text PDFAn Unusual, Symmetric Rash on Both Forearms in a 94-Year-Old Patient A Clinicopathological Challenge and Diagnostic Pitfall.
J Cutan Pathol
February 2025
Department of Dermatology, University Hospital Basel, Basel, Switzerland.
Article Synopsis
- Trichophyton rubrum (T. rubrum) typically causes minor skin infections, mostly affecting healthy individuals, but can lead to serious infections in immunocompromised patients.
- A unique case involved a 94-year-old man with an invasive T. rubrum infection on both forearms, which resembled cutaneous blastomycosis.
- Diagnosis is complicated as T. rubrum can present with large spore-like structures that mimic Blastomyces dermatitidis, underscoring the necessity for culture or PCR testing for accurate identification.
Acquired ectopic nail: A case report in an 18-year-old female with traumatic onset.
Int J Surg Case Rep
November 2024
Department of Dermatology, Faculty of Medicine, University of Aleppo, Aleppo, Syria.
Introduction And Importance: Post-traumatic ectopic nail (PTEN) refers to the abnormal growth of a new nail in a site other than the usual one, typically occurs after a trauma to the nail matrix. The exact pathogenesis is still unknown. This rare condition often affects the dorsal aspect of the phalanx.
View Article and Find Full Text PDFNail pitting in an infant with Kawasaki disease-A novel clinical finding.
Int J Rheum Dis
September 2024
Pediatric Allergy Immunology Unit, Department of Pediatrics, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Article Synopsis
- Kawasaki disease can cause various nail changes in children, such as Beau's lines, leukonychia, and orange-brown chromonychia during recovery.
- Nail pitting, which is common in other conditions, is rare in Kawasaki disease cases.
- The text presents a unique case of nail pitting occurring in a child with Kawasaki disease.
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