Equine group A rotavirus (RVA) strain H-1 (RVA/Horse-tc/GBR/H-1/1975/G5P9[7]) was found to have VP4, VP6-7, NSP1 and NSP4 genes of porcine origin. In order to obtain conclusive information on the exact origin and evolution of this unusual equine strain, the remaining six genes (VP1-3, NSP2-3 and NSP5 genes) of strain H-1 were analyzed in the present study. By whole genomic analysis, strain H-1 exhibited a porcine RVA-like genotype constellation (G5-P[7]-I5-R1-C1-M1-A8-N1-T1-E1-H1), different from those of typical equine RVA strains. The VP2-3 and NSP2-3 genes of strain H-1 were found to originate from porcine RVAs. On the other hand, it was difficult to pinpoint the exact origin of the VP1 and NSP5 genes of strain H-1, though phylogenetically, these genes appeared to be possibly derived from porcine or Wa-like human strains. Taken together, at least nine (VP2-4, VP6-7 and NSP1-4 genes) of the 11 gene segments of strain H-1 were found to be of porcine origin, revealing a porcine RVA-like genetic backbone. Therefore, strain H-1 is likely a porcine RVA strain that was transmitted to horses.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.vetmic.2012.02.037 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A parallel bioreactor strategy to rapidly determine growth-coupling relationships for bioproduction: a mevalonate case study.
Biotechnol Biofuels Bioprod
January 2025
Manchester Institute of Biotechnology, The University of Manchester, 131 Princess Street, Manchester, M1 7DN, UK.
Background: The climate crisis and depleting fossil fuel reserves have led to a drive for 'green' alternatives to the way we manufacture chemicals, and the formation of a bioeconomy that reduces our reliance on petrochemical-based feedstocks. Advances in Synthetic biology have provided the opportunity to engineer micro-organisms to produce compounds from renewable feedstocks, which could play a role in replacing traditional, petrochemical based, manufacturing routes. However, there are few examples of bio-manufactured products achieving commercialisation.
View Article and Find Full Text PDFDecoding the Hume-Rothery Rule in a Bifunctional Tetra-metallic Alloy for Alkaline Water Electrolysis.
Nano Lett
January 2025
Department of Chemical Sciences, and Centre for Advanced Functional Materials, Indian Institute of Science Education and Research (IISER) Kolkata, Mohanpur 741246, India.
The 90-year-old Hume-Rothery rule was adapted to design an outstanding bifunctional tetra-metallic alloy electrocatalyst for water electrolysis. Following the radius mismatch principles, Fe (131 pm) and Ni (124 pm) are selectively incorporated at the Pd (139 pm) site of MoPd nanosheets. Analogously, Cu (132 pm) alloys with only Pd, while Ag (145 pm) alloys with both Pd and Mo (154 pm).
View Article and Find Full Text PDFProduction of polyhydroxybutyrate with high cell density cultivation using thermophile Caldimonas thermodepolymerans.
Bioresour Technol
January 2025
This study investigates the production of polyhydroxybutyrate (PHB) using the thermophilic bacterium Caldimonas thermodepolymerans in fed-batch fermentation. This research highlights the potential of thermophilic bacteria in biopolymer production due to their ability to operate at high temperatures, which reduces contamination risks and enhances energy efficiency. Optimal fermentation conditions were identified at a temperature of 50 °C, with the strain achieving a maximum specific growth rate (μ) of 0.
View Article and Find Full Text PDFSite-Specific for CO Photoreduction with Single-Atom Ni on Strained TiO Derived from Bimetallic Metal-Organic Frameworks.
Small
January 2025
College of Materials Science and Engineering, Qingdao University of Science and Technology, Qingdao, 266042, P. R. China.
The photocatalytic reduction of CO in water to produce fuels and chemicals is promising while challenging. However, many photocatalysts for accomplishing such challenging task usually suffer from unspecific catalytic active sites and the inefficient charge carrier's separation. Here, a site-specific single-atom Ni/TiO catalyst is reported by in situ topological transformation of Ni-Ti-EG bimetallic metal-organic frameworks.
View Article and Find Full Text PDFThe objective of this study was to investigate the effect of the () SS18-50 (an isolate with favorable probiotic properties following space traveling) on dextran sulfate sodium (DSS)-induced colitis in mice. Male ICR mice were randomly assigned to one of six groups: a control group, a model group, and four intervention groups comprising the isolate (SS18-50-L and SS18-50-H) and the wild type (GS18-L and GS18-H) strains. The model group and the intervention groups were administered a 3.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!