The aim of this study was to determine the reliability and discriminant validity of the Dutch version of the life satisfaction questionnaire (Lisat-9 DV) to assess patients with an acquired brain injury. The reliability study used a test-retest design, and the validity study used a cross-sectional design. The setting was the general rehabilitation centre. There were 159 patients over 18 years of age, with an acquired brain injury, in the chronic phase. The main outcome measures were weighted κ of test and retest data on the nine questions of the Lisat-9 DV and significance levels of differences between subgroups of patients who are expected to differ in terms of Lisat-9 scores, on the basis of other instruments. The results were as follows: the reliability was moderate, with the weighted κ ranging from 0.41 to 0.64. In terms of validity, subgroups of patients who were expected to differ in terms of the Lisat-9 domains did indeed differ significantly, except for the difference in the Lisat score for 'contact with friends and acquaintances' between subgroups defined by higher or lower scores on the corresponding domain of the Frenchay Activities Index. As there was a plausible explanation for not finding a significant difference between subgroups defined by one of the Frenchay Activities Index domains and significant differences were found between the subgroups defined by other instruments corresponding to the same domain, we conclude that the discriminant validity is good. The reliability was not clearly affected by cognitive disorder or aphasia. The conclusions were that the reliability of the Lisat-9 DV for patients with an acquired brain injury was moderate; the discriminant validity was good.
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http://dx.doi.org/10.1097/MRR.0b013e328352ab28 | DOI Listing |
Curr Alzheimer Res
January 2025
Student's Scientific Research Center, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Background: Alzheimer's disease (AD) is a progressive neurodegenerative condition with rising prevalence due to the aging global population. Existing methods for diagnosing AD are struggling to detect the condition in its earliest and most treatable stages. One early indicator of AD is a substantial decrease in the brain's glucose metabolism.
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January 2025
Department of Radiology, Aerospace Center Hospital, Beijing, China.
Background: Acupuncture has been demonstrated to have a promising effect on Alzheimer's disease (AD), but the underlying neural mechanisms remain unclear. The retrosplenial cortex (RSC) is one of the earliest brain regions affected in AD, and changes in its functional connectivity (FC) are reported to underlie disease-associated memory impairment. The aim of this study was to examine the effect of acupuncture on FC with the RSC in patients with AD.
View Article and Find Full Text PDFBrain Inj
January 2025
Cognitive Neuroscience Unit, School of Psychology, Deakin University, Geelong, Australia.
Introduction: Magnetic resonance imaging (MRI) has revolutionized our capacity to examine brain alterations in traumatic brain injury (TBI). However, little is known about the level of implementation of MRI techniques in clinical practice in TBI and associated obstacles.
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Brain Inj
January 2025
Department of Nursing, Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Background: Informal caregivers of individuals with acquired brain injury (ABI) often lack adequate preparedness for caregiving. Caregiver burden may reduce preparedness, with anxiety potentially mediating this relationship. However, these associations remain unclear.
View Article and Find Full Text PDFProc Biol Sci
January 2025
Graduate School of Integrated Science and Technology, Shizuoka University, Hamamatsu 432-8011, Japan.
The brain optimizes timing behaviour by acquiring a prior distribution of target timing and integrating it with sensory inputs. Real events have distinct temporal statistics (e.g.
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