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Expression of Tissue Remodeling- and Inflammation-Related Factors During the Wound-Healing Process in Humans.
J Pers Med
January 2025
Second Department of Propaedeutic Surgery, "Laiko" General Hospital of Athens "Laiko", Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
: There is a growing interest in the research of wound healing mechanisms worldwide. Particular attention has been paid to the expression of tissue remodeling- and inflammation-related factors. Herein, we investigate the expression patterns of TGF-β1, IL-6, TNF-a, uPA, uPA receptors, MMP-2, and MMP-9 through the four phases of the normal wound-healing process in humans.
View Article and Find Full Text PDFRetrospective registry-based nationwide analysis of the COVID-19 lockdown effect on the volume of general and visceral non-malignant surgical procedures.
Surg Pract Sci
June 2024
Division of Trauma Surgery, Department of Traumatology, University Hospital Zurich, University Zurich, Switzerland.
Introduction: Coronavirus disease 2019 (COVID-19) is an acute virus infection, which was declared a pandemic by the World Health Organization. The Swiss government decreed a public lockdown to reduce and restrict further infections. The aim of this investigation was to analyze the impact of the first COVID-19 lockdown on the performance of general and visceral surgery procedures.
View Article and Find Full Text PDFConcurrent pilonidal sinus of the nape of the neck and sacrococcygeal region.
BMJ Case Rep
January 2025
General Surgery, MS Ramaiah Medical College, Bangalore, Karnataka, India.
The most common site for a pilonidal sinus is the sacrococcygeal region, typically affecting hirsute males. Hair entrapment beneath the skin triggers a granulomatous reaction, leading to the formation of a sinus tract. Here, we present a rare case of concurrent pilonidal abscess in both the nape of the neck and the natal cleft.
View Article and Find Full Text PDFEvaluating efficacy and outcomes: comparison of laser treatment and crystallized phenol in pilonidal sinus disease.
Front Surg
January 2025
Department of General Surgery, Atılım University Faculty of Medicine, Ankara, Türkiye.
Objective: The aim of this study is to comprehensively evaluate the efficacy of laser ablation and crystallized phenol application in the treatment of pilonidal sinus disease, focusing on treatment success, recurrence rates, complications, and the patients' return to normal life.
Material And Method: Data from patients treated for pilonidal sinus disease with laser ablation and crystallized phenol application at our clinic between January 2020 and September 2023 were retrospectively reviewed. Preoperative data including pit counts, disease stage, preoperative pilonidal abscess history, disease duration (week), treatment success, recurrence/persistent disease, postoperative complications, healing time (days), and visual analogue scale (VAS) scores on postoperative days 1 and 7, as well as return to normal life (days), were analyzed.
Chronic interdigital pilonidal sinus caused by dog hair.
BMJ Case Rep
January 2025
Department of Pathology, NHS Dumfries and Galloway, Dumfries, Dumfries and Galloway, UK.
We present a male patient in his early 70s with a cyclical 20-year history of a nodular papule affecting the left forefoot. On examination, ginger red-coloured hairs were evident within the sinus tract, correlating with the patient's short-haired Hungarian Vizsla dogs. Histology confirmed the diagnosis of pilonidal sinus.
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