Facile, rapid and efficient biofabrication of gold nanoparticles decorated with functional proteins.

Analyst

Division of Environment and Radiation Sciences, Nuclear Science and Engineering Directorate, Japan Atomic Energy Agency, Tokai-mura, Ibaraki 319-1195, Japan.

Published: May 2012

We report a one-pot biological approach to fabricate gold nanoparticle (AuNP)-ZZ domain conjugates using peptide-functionalized proteins that can simultaneously direct both biomineralization and surface modification of AuNPs. In addition, immuno-AuNPs are readily prepared through the specific binding of antibodies to the ZZ domain on the AuNPs.

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http://dx.doi.org/10.1039/c2an35172bDOI Listing

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