Aims: Right ventricular (RV) function has important prognostic and therapeutic implications. Assessment of RV function using echocardiography is challenging. The aim of this study was to evaluate a new parameter of RV function, right ventricular outflow tract systolic excursion (RVOT_SE).
Methods And Results: RVOT_SE was measured using M-Mode echocardiography from the parasternal short-axis view at the level of the aortic valve, and was defined as the systolic excursion of the RVOT anterior wall. RVOT_SE was measured in 50 patients (age 64 ± 18 years, 28 males) with normal RV function [RV fractional area change (FAC) ≥35% and tricuspid annular plane systolic excursion (TAPSE) ≥1.6 cm] and 40 patients (age 68 ± 12 years, 35 males) with reduced RV function (RV FAC <35% and TAPSE <1.6 cm). R.V FAC was 46 ± 7% in the normal RV group and 22 ± 5% in the reduced RV group (P < 0.0001). TAPSE was 2.2 ± 0.4 cm in the normal RV group and 1.0 ± 0.2 cm in the reduced RV group (P < 0.0001). RVOT_SE was 9.6 ± 1.5 mm in the normal RV group and 1.7 ± 1.1 mm in the reduced RV group (P < 0.0001). RVOT_SE <6 mm identified patients with reduced RV function with 100% sensitivity and 100% specificity. Survival at 1 year was 63% in patients with RVOT_SE <6 mm and 84% in patients with RVOT_SE ≥6 mm, P = 0.004.
Conclusion: RVOT_SE is a novel, simple, and promising parameter for assessing RV function, and it is associated with poor survival.
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http://dx.doi.org/10.1093/ehjci/jes055 | DOI Listing |
Int J Rheum Dis
January 2025
Department of Rheumatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
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View Article and Find Full Text PDFJ Cardiol
January 2025
Department of Cardiovascular Medicine, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.
Right ventricular (RV) longitudinal strain has emerged as a crucial tool for evaluating RV systolic function in patients with heart disease. The complex anatomy of the RV presents challenges for functional assessment, traditionally conducted using conventional parameters, such as tricuspid annular plane systolic excursion and RV fractional area change. While these conventional methods are simple and practical, they have limitations in reflecting the majority of global RV systolic function.
View Article and Find Full Text PDFObjective: ADHD is one of the most common neurodevelopmental disorders, seen in children and adolescents, and is often treated with various pharmacological agents, especially methylphenidate. There are differing opinions in the literature regarding the cardiovascular safety of long-term methylphenidate use. Studies suggest that the drug may increase the risk of hypertension, myocardial infarction, ventricular arrhythmia, sudden cardiac death, cardiomyopathy, heart failure (HF), pulmonary hypertension, and stroke.
View Article and Find Full Text PDFJ Cardiothorac Surg
December 2024
Department of Cardiology, Thomas Jefferson University, Philadelphia, PA, 19107, USA.
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View Article and Find Full Text PDFJ Cardiovasc Dev Dis
December 2024
Institute of Cardiovascular Sciences, University of Birmingham, Birmingham B15 2TT, UK.
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