Corneal wound healing is divided into several phases that, in reality are part of a continuous process, involving the corneal epithelium and stroma, corneal nerves, inflammatory cells, lacrimal glands. The layers of the cornea interact through autocrine and paracrine modulation, mediated by cytokines, growth factors, proteolytic enzymes. Corneal healing is affected by many factors, including: wound size and depth, causative agent, age, medication, preexisting diseases.
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