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[Preservation of parenchymal and stromal progenitors in cryopreserved human fetal liver]. | LitMetric

AI Article Synopsis

  • The study demonstrates the existence of hepatoblasts and other cell types in cryopreserved human fetal liver suspension cells.
  • There is evidence of epithelial-mesenchymal transition occurring in hepatoblasts when cultured.
  • The research suggests that the cryopreservation technique used for hematopoietic cells can also be applied to preserve parenchymal and stromal cells from the fetal liver during the first trimester.

Article Abstract

In this paper we show presents of viable population of hepatoblasts, endodermal blasts, endothelial and mesenchymal cells in the cryopreserved suspension cells of human fetal liver. Also we observed epithelial-mesenchymal transition of hepatoblasts in culture. We show that it's possible to apply the method of cryopreservation of hematopoietic cells of human fetal liver of the first gestation trimester for cryopreservation of parenchymal and stromal cells of fetal liver.

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