Lymphatic filariasis in a rural community in Nigeria: a challenge ahead.

Afr J Med Med Sci

Department of Medical Microbiology and Parasitology, Ladoke Akintola University of Technology, PM.B. 4400 Osogbo, Osun State, Nigeria.

Published: December 2010

Lymphatic filariasis (LF) represents a major public health problem in tropical and subtropical regions of the world. Following the admission of a 65 year old man from Sowo village Abeokuta Ogun State with a case of LF at the Federal Medical Centre Abeokuta, a cross-sectional based survey was carried out to determine the occurrence and prevalence of LF in this village. Identification of the LF parasite was carried out with blood stained with Giemsa and examined under low power magnification for the presence of sheathed microfilaria. Out of 317 persons examined 54 (17%) were microfilaraemic and their ages varied from 10 to 70 years. The age group 40-49 has the highest prevalence of 36.5% and highest mean microfilaria count of 4.8mf/mL. In the age group 20-29, females (12.8%) were more infected than males (9.3%) and the difference was statistically significant (P=0.0042). In all more males (17.8%) were affected than females (16.9%) (P=0.9481) and the mean MF count in males (22.8mf/ML) was higher than females (21.7mf/ML). The prevalent rate of elephantiasis and hydrecoele observed in the community was 2.2% respectively. The result of this study confirms and observed a high prevalence rate of LF in this community. This finding establishes the need for Ministry of Health (MOH) and Global Alliance to Eliminate LF (GAELF) to carry out disease control activities through Annual Mass Drug Administration (MDA) in this community.

Download full-text PDF

Source

Publication Analysis

Top Keywords

lymphatic filariasis
8
age group
8
filariasis rural
4
community
4
rural community
4
community nigeria
4
nigeria challenge
4
challenge ahead
4
ahead lymphatic
4
filariasis represents
4

Similar Publications

Objectives: Zimbabwe is endemic for lymphatic filariasis (LF) with 39 districts identified for mass drug administration (MDA) in 2014. The objective of this study was to reassess the current population requiring MDA.

Methods: The LF confirmatory mapping method was used to evaluate the prevalence of circulating filarial antigens (CFA) among school-aged children (9-14 years) in previously endemic districts.

View Article and Find Full Text PDF

Evaluating stakeholder coordination and partnerships for NTD elimination in Taraba state, Nigeria: a multi-level analysis.

BMC Infect Dis

January 2025

Pan-African Community Initiative on Education and Health (PACIEH), Ekulu West GRA, No. 8 Somto Anugwom Close, Enugu, Enugu State, 400102, Nigeria.

Introduction: Nigeria has a significant burden of NTDs with more than 120 million people at risk of the dominant NTDs namely Lymphatic Filariasis, Onchocerciasis, and Schistosomiasis. Control efforts have involved the four levels of governance with programs focused on vector control, preventive chemotherapy, water, sanitation and health education. However, the coordination across these levels and with multiple stakeholders remains unclear especially in states like Taraba that have received significant funding from local non-governmental organisations.

View Article and Find Full Text PDF

Background: WHO recommends two annual rounds of mass drug administration (MDA) with ivermectin, diethylcarbamazine, and albendazole (IDA) for lymphatic filariasis (LF) elimination in treatment naïve areas that are not co-endemic for onchocerciasis such as Papua New Guinea (PNG). Whether two rounds of MDA are necessary or sufficient and the optimal sampling strategies and endpoints for stopping MDA remain undefined.

Methods And Findings: Two cross-sectional studies were conducted at baseline (N = 49 clusters or villages) and 12 months after mass drug administration (MDA) with IDA (N = 47 villages) to assess lymphatic filariasis (LF) by circulating filarial antigenemia (CFA) and microfilariae (Mf).

View Article and Find Full Text PDF

Objectives: Lymphatic filariasis (LF) elimination efforts in Ghana have been ongoing since 2001, achieving substantial progress through mass drug administration (MDA). However, despite significant advances, LF transmission persists in certain areas. Some districts previously classified as non-endemic have reported lymphedema and hydrocele cases, raising concerns about LF endemicity.

View Article and Find Full Text PDF

Accurate rapid diagnostic tests (RDTs) are needed to diagnose lymphatic filariasis (LF) in global elimination programmes. We evaluated the performance of the new STANDARD Q Filariasis Antigen Test (QFAT) against the Bioline Filariasis Test Strip (FTS) for detecting antigen (Ag) in laboratory conditions, using serum (n = 195) and plasma (n = 189) from LF-endemic areas (Samoa, American Samoa and Myanmar) and Australian negative controls (n = 46). The prior Ag status of endemic samples (54.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!