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A novel synthetic strategy for monosubstituted cyclodextrin derivatives. | LitMetric

A novel synthetic strategy for monosubstituted cyclodextrin derivatives.

Chem Commun (Camb)

Dipartimento di Scienze Chimiche, Università degli Studi di Napoli Federico II, Complesso Universitario di Monte S. Angelo, via Cintia, 4, I-80126 Napoli, Italy.

Published: April 2012

A first solid phase approach to obtain monosubstituted CD conjugates to different labels has been developed. A new solid support has been designed to get a variety of C-6 monofunctionalized CDs (α, β, MeβCD and HPβCD) covalently linked through a phosphodiester bridge to different labels, in highly pure form and under very mild detachment conditions.

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Source
http://dx.doi.org/10.1039/c2cc30550jDOI Listing

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