In the asymmetric unit of the title compound, C(18)H(20)N(2)O(5), there are two crystallographic independent mol-ecules. Both mol-ecules are twisted; the dihedral angle between the two benzene rings is 7.2 (5)° in one mol-ecule, whereas it is 85.9 (4)° in the other. Of the three meth-oxy groups in the 3,4,5-trimeth-oxy-phenyl unit, two meth-oxy groups at meta positions are approximately coplanar with the benzene plane [C-O-C-C torsion angles of -2.3 (13)-4.8 (11)°], but the other meth-oxy, at the para position, is out of the plane [C-O-C-C of 72.8 (9)° in one mol-ecule and -77.5 (9)° in the other]. In the crystal, mol-ecules are linked by N-H⋯O hydrogen bonds and weak C-H⋯O inter-actions into tapes along the b axis. C-H⋯π inter-actions are also present.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297292PMC
http://dx.doi.org/10.1107/S1600536812003534DOI Listing

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