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Biodistribution and radiodosimetry of a novel myocardial perfusion tracer 123I-CMICE-013 in healthy rats.
EJNMMI Res
March 2014
Nordion Inc, 447 March Road, Ottawa, ON K2K 1X8, Canada.
Background: 123I-CMICE-013 is a novel radiotracer previously reported to have promising characteristics for single-photon emission computed tomography (SPECT) myocardial perfusion imaging. We evaluated the biokinetics and radiodosimetry of this rotenone-like 123I-labeled tracer in a microSPECT imaging-based study.
Methods: 37 to 111 MBq of 123I-CMICE-013 was synthesized and administered intravenously to 14 healthy rats.
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