Photolocalized purpura during levofloxacin therapy.

Photodermatol Photoimmunol Photomed

Department of Clinical Medicine and Immunological Sciences, Dermatology Section, University of Siena, Siena, Italy.

Published: April 2012

Side-effects associated with levofloxacin treatment include phototoxicity, hypersensitivity and skin disorders. Purpuric eruptions have rarely been reported. We describe the case of a 75-year-old woman who was prescribed a 15-day course of levofloxacin (500 mg twice a day) for hemorrhagic cystitis. On exposure to sunlight, the patient developed a pruritic purpuric eruption on the lower extremities. The acute reaction differed from a classical sunburn, manifesting as confluent petechiae limited to sun-exposed areas and accompanied by pruritus. This was a rare case of solar capillaritis. Purpuric eruptions on photoexposed skin should be considered another unusual side effect of levofloxacin.

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http://dx.doi.org/10.1111/j.1600-0781.2012.00646.xDOI Listing

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