Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.carj.2011.10.001 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
An update on selective estrogen receptor modulator: repurposing and formulations.
Naunyn Schmiedebergs Arch Pharmacol
January 2025
Department of Pharmaceutics & Pharmaceutical Technology, Shree S. K. Patel College of Pharmaceutical Education & Research, Ganpat University, Kherva, Gujarat, 384012, India.
The selective estrogen receptor modulator (SERM) raloxifene hydrochloride (RLH) is used extensively in the management and prevention of breast cancer and osteoporosis. Recent clinical studies show the repurposing of RLH in various diseases based on its structure and some clinical trials studies. Optimizing the clinical effectiveness of this important drug requires a thorough review of the formulation techniques, patent environment, and analytical procedures.
View Article and Find Full Text PDFDeep Learning-Based Pointer Meter Reading Recognition for Advancing Manufacturing Digital Transformation Research.
Sensors (Basel)
January 2025
School of Mechanical Engineering, Sichuan University, Chengdu 610065, China.
With the digital transformation of the manufacturing industry, data monitoring and collecting in the manufacturing process become essential. Pointer meter reading recognition (PMRR) is a key element in data monitoring throughout the manufacturing process. However, existing PMRR methods have low accuracy and insufficient robustness due to issues such as blur, uneven illumination, tilt, and complex backgrounds in meter images.
View Article and Find Full Text PDFClinical efficacy of OS-01 peptide formulation in reducing the signs of periorbital skin aging.
Int J Cosmet Sci
January 2025
Genomic Sciences and Biotechnology Program, Catholic University of Brasilia, Brasília, Federal District, Brazil.
Background: The aging of the skin, particularly around the periorbital region, is a complex process characterized by the accumulation of senescent cells, decreased collagen production, and reduced skin elasticity, leading to visible signs such as fine lines, wrinkles, and sagging.
Objective: This study investigates the efficacy of a novel topical formulation, OS-01 EYE, containing the senomorphic peptide, OS-01, along with other active ingredients, in improving the skin around the eyes.
Methods: A 12-week clinical study was conducted with 22 participants who applied OS-01 EYE twice daily.
Specificity and sensitivity of ALT-associated markers in cancer cells.
FEBS Lett
January 2025
Dipartimento di Scienze, Università degli Studi "Roma Tre", Italy.
Some tumors employ a mechanism called alternative lengthening of telomeres (ALT) to counteract telomere shortening-induced replicative senescence. Several hallmarks are used to identify cell lines and tumors as ALT-positive. Here, we analyzed a panel of ALT-positive and -negative cancer cell lines to investigate the specificity and sensibility of ALT-associated markers.
View Article and Find Full Text PDFDesign and Optimization of Isothermal Gene Amplification for Generation of High-Gain Oligonucleotide Products by MicroRNAs.
ACS Meas Sci Au
December 2024
Department of Bioengineering and Nano-Bioengineering, Research Center for Bio Materials and Process Development, Incheon National University, Incheon 22012, Republic of Korea.
Thermal cycling-based quantitative polymerase chain reaction (qPCR) represents the gold standard method for accurate and sensitive nucleic acid quantification in laboratory settings. However, its reliance on costly thermal cyclers limits the implementation of this technique for rapid point-of-care (POC) diagnostics. To address this, isothermal amplification techniques such as rolling circle amplification (RCA) have been developed, offering a simpler alternative that can operate without the need for sophisticated instrumentation.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!