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http://dx.doi.org/10.1111/j.1610-0387.2012.07910.x | DOI Listing |
Appl Environ Microbiol
January 2025
Department of Biological Sciences, Minnesota State University Mankato, Mankato, Minnesota, USA.
Unlabelled: causes bacterial cold-water disease (BCWD) in salmonids and other fish, resulting in substantial economic losses in aquaculture worldwide. The mechanisms uses to cause disease are poorly understood. Despite considerable effort, most strains of have resisted attempts at genetic manipulation.
View Article and Find Full Text PDFThe emergence of artificial intelligence (AI) in drug discovery represents a transformative development in addressing neglected diseases, particularly in the context of the developing world. Neglected diseases, often overlooked by traditional pharmaceutical research due to limited commercial profitability, pose significant public health challenges in low- and middle-income countries. AI-powered drug discovery offers a promising solution by accelerating the identification of potential drug candidates, optimising the drug development process, and reducing the time and cost associated with bringing new treatments to market.
View Article and Find Full Text PDFJ Otol
October 2024
Law at China University of Geosciences (Beijing), No.29 Xueyuan Road, Haidian District,Beijing,100083, China.
Under the background of medical disputes growing in number, scale and intensity, tracing back legal changes in medical field as a breakthrough point, this paper took a legal perspective to illustrate changes in medical dispute settlements from legislative orientation to legal system improvement. In view of the fact that early legislation in medical field was biased towards identification and punishment of doctors' responsibility, and later intensive legislation in balancing increasing "medical trouble" phenomenon with limited effects and difficulties to abide by the law, this paper proposed to improve doctor-patient dispute settlements system in China referencing from foreign law experience, to reduce investigation of doctors at the judicial level, and to establish a settlement mechanism on doctors' apology at the legislative level, so as to promote a healthy development of doctor-patient relationship.
View Article and Find Full Text PDFActa Orthop
January 2025
Department of Orthopaedics, Leiden University Medical Center, Leiden, The Netherlands.
Background And Purpose: This study updates 2 parallel systematic reviews and meta-analyses from 2012, which established the 1-year radiostereometric (RSA) migration thresholds for tibial components of total knee replacements (TKR) based on the risk of late revision for aseptic loosening from survival studies. The primary aim of this study was to determine the (mis)categorization rate of the 2012 thresholds using the updated review as a validation dataset. Secondary aims were evaluation of 6-month migration, mean continuous (1- to 2-year) migration, and fixation-specific thresholds for tibial component migration.
View Article and Find Full Text PDFPLoS One
January 2025
School of Public Health & Community Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Introduction: Low- and middle-income countries experience high injury-related mortality rates, with road traffic crashes being a significant contributor in Nigeria. Data from trauma registries are crucial for designing and advocating for trauma intervention programmes. However, there is limited research to inform the development of trauma registries in a Nigerian setting.
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