The present clinical and laboratory study of the effects of general air cryogenic therapy on the characteristics of blood supply included practically healthy subjects. The study has demonstrate that dosed cold stress promotes adaptive capacities of the organism by modulating the oxygen-transporting function of the blood that in its turn stimulates the adaptive mechanisms and leads to decoupling tissue respiration. It is concluded that general air cryogenic therapy can be recommended as an instrument for the improvement of endurance of and resistibility to the action of hypoxemia in special groups of people under the low temperature conditions.

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