AI Article Synopsis

  • A new copper-catalyzed method has been developed for creating phenol-derived compounds, specifically 1-bromoenol ethers, ynol ethers, and ketene acetals.
  • This process involves a cross-coupling reaction that is efficient and can be applied to various substrates.
  • The main reactants used are easily accessible 1,1-dibromo-1-alkenes and phenols, making the method practical for synthetic chemistry.

Article Abstract

An efficient and general copper-catalyzed method is reported for the synthesis of phenol-derived 1-bromoenol ethers, ynol ethers, and ketene acetals by chemodivergent copper-catalyzed cross-coupling between readily available 1,1-dibromo-1-alkenes and phenols.

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Source
http://dx.doi.org/10.1021/ol300491dDOI Listing

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