AI Article Synopsis
- The paper discusses how representation and measurement in genetic circuits influence the reliability of engineered systems.
- The authors propose a design scheme using continuous computation to tackle these challenges.
- They illustrate their methodology by applying a computer architecture concept (branch prediction) in biological contexts, with simulations demonstrating its feasibility for future laboratory testing.
Article Abstract
In this paper we consider the problem of representation and measurement in genetic circuits, and investigate how they can affect the reliability of engineered systems. We propose a design scheme, based on the notion of continuous computation, which addresses these issues. We illustrate the methodology by showing how a concept from computer architecture (namely, branch prediction) may be implemented in vivo, using a distributed approach. Simulation results confirm the in-principle feasibility of our method, and offer valuable insights into its future laboratory validation.
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| http://dx.doi.org/10.1016/j.biosystems.2012.02.001 | DOI Listing |
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