AI Article Synopsis

  • * A systematic review of literature identified 7 relevant studies, showing that patients generally had low average to average IQ scores pre-surgery and around an 85% success rate in seizure control post-surgery (Engel Class I outcome).
  • * In a case series of 13 children, most demonstrated stable neuropsychological functioning after surgery, with only a few showing significant changes, though about one-third experienced psychological improvements.

Article Abstract

Rationale: The purposes of this study were to 1) conduct a review of neuropsychological (NP) outcomes after epilepsy surgery for DNET and 2) present pre/post-surgical NP results from a series of children with DNET.

Methods: First, a systematic literature review was conducted with specific inclusion criteria. Second, a review of DNET surgical patients seen at two tertiary-care hospitals using reliable change methods of NP functioning was conducted.

Results: Of 300 citations retrieved, 7 studies met criteria. Studies reported low average to average pre-surgical IQ. Engel Class I outcome was approximately 85%.

Case Series: Thirteen children completed pre/post-surgical NP assessments. Pre-surgically, children demonstrated low average to average functioning. Post-surgically, few patients showed reliable change. One-third of children demonstrated psychological improvement.

Conclusions: NP outcome following DNET has not been well-described. Children with DNET demonstrate low average to average NP functioning pre-surgically, good seizure outcome, and stable NP functioning post-surgically.

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Source
http://dx.doi.org/10.1016/j.yebeh.2011.12.011DOI Listing

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