iPSCs to the rescue in Alzheimer's research.

Cell Stem Cell

Genetics and Aging Research Unit, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.

Published: March 2012

A crucial limitation to our understanding of Alzheimer's disease has been the inability to test hypotheses on live, patient-specific neurons. A recent study in Nature by Israel et al. (2012) reports that iPSC-derived neurons from AD patients recapitulate multiple aspects of disease pathology.

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Source
http://dx.doi.org/10.1016/j.stem.2012.02.011DOI Listing

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