Rates of synthesis and degradation of monoamines, acetyl choline and protein were distinctly altered in cortex-subcortex structures of the brain locomotory system after a single administration of tetrapeptide tuftsin Thr-Lys-Pro-Arg during the period 15-30 min of its pronounced effect on the animal motor activity. Correlation between the functional and morphological alterations in cellular and subcellular brain structures, caused by the peptide administration, is discussed.

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