Aim: To evaluate whether the inclusion of advice in the hospital discharge letter regarding published guidelines for the review of PPI therapy can increase the number of patients that have documented PPI therapy review, consistent with the published guidelines, following hospital discharge.
Method: Patients on PPIs at discharge from hospital were randomised to either have their hospital discharge letter completed as per usual practice or to have additional information on PPI review included that was aligned to published local guidelines. Patients' GP records were reviewed at 3 to 6 months post discharge to determine if a PPI review had occurred and if that review adhered to the guidelines.
Results: Including specific, guideline based, PPI discharge instructions in the hospital discharge summary did not significantly increase the number of patients receiving post-discharge review consistent with the guidelines. Post discharge only 5/26 (19%) patients in the control group and 6/25 (24%) in the intervention group had their PPI therapy reviewed in accordance with the guidelines.
Conclusion: We were not able to demonstrate a beneficial change in PPI prescribing practice from the inclusion of PPI prescribing advice in the discharge letter.
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Drug Alcohol Depend Rep
December 2024
Banner - University Medical Center South, 2800 Ajo Way, Tucson, AZ 85713, United States.
Background: There are many barriers to prescribing medications for opioid use disorder (MOUD). This study evaluates the prevalence, patterns, and predictors of inpatient MOUD prescribing at discharge to patients with a diagnosis of opioid use/opioid use disorder (OUD) that developed opioid withdrawal during their hospital stay.
Methods: This multicenter, retrospective cross-sectional study occurred at three hospitals in Arizona.
Front Pediatr
December 2024
Pediatric Rheumatology Department, Hospital Para El Niño Poblano, Puebla, Mexico.
A female patient in middle childhood was diagnosed with coarctation of the aorta at one month of age and underwent a successful cortectomy. At 11 years old, she developed re-coarctation, which was managed through interventional cardiology. Shortly after the procedure, she experienced a sudden and severe clinical decline, presenting with hypoperfusion of the lower extremities, gastrointestinal bleeding, acute kidney injury, and pancreatitis.
View Article and Find Full Text PDFFront Immunol
December 2024
Diretoria de Ensino e Pesquisa, Fundação de Medicina Tropical Dr Heitor Vieira Dourado, Manaus, AM, Brazil.
Background: In SARS-CoV-2 infection, cytokines and laboratory biomarkers play a key role in disease progression and their long-term levels have been associated with the outcome of long COVID-19.
Objectives: I) study the levels of cytokines, hematological and biochemical biomarkers in the acute and post-acute phases of COVID-19 disease; and II) assess the impact of COVID-19 vaccine doses on fatigue symptoms.
Methods: This study is an exploratory cohort nested within a clinical and laboratory follow-up of surviving participants after pre-vaccine acute COVID-19 infection with severe clinical manifestations.
Trans R Soc Trop Med Hyg
January 2025
Department of Cardiology and Cardiovascular Surgery, Faculdade de Medicina de São José do Rio Preto, SP, 15090-000, Brazil.
Background: Immunological similarities led us to explore potential interactions between Chagas heart disease (CHD) and coronavirus disease 2019 (COVID-19). We evaluated CHD's impact on the short- and long-term clinical courses of COVID-19 patients.
Methods: The CHD group comprised consecutive hospitalized patients (March 2020-March 2022), while the controls were selected through genetic matching based on COVID complications predictors.
Clin Rehabil
January 2025
Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Objective: To identify factors, present at 3 months after COVID-19 that are associated with the level of functioning 1 year after hospitalization.
Design: Multicenter prospective observational study.
Setting: Region Västra Götaland Sweden.
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