AI Article Synopsis
- The study explores the relationship between mean platelet volume (MPV) levels and varicocele in 60 affected individuals compared to 57 healthy controls.
- Significant findings show that MPV levels are higher in varicocele patients, with a notable correlation between MPV, varicocele grade, and the size of the left spermatic vein.
- The research concludes that elevated MPV is linked to varicocele severity and indicates a potential role of vascular factors in the condition's development, suggesting further investigation into platelet behavior in varicocele patients.
Article Abstract
Objective: To examine the relationship between the mean platelet volume (MPV) and varicocele to clarify the etiopathogenesis of varicocele.
Methods: MPV levels were measured in 60 varicocele subjects (group I) and 57 healthy controls (group II) from 2009-2010. Ages were similar between the 2 groups. The diagnosis of varicocele was based on the findings from both physical examination and color Doppler ultrasound.
Results: The average patient age at the time of examination was 28.12 ± 6.4 years in group I and 28.10 ± 5.8 in group II. MPV levels were statistically significantly higher in group I than in group II (P < .001). Positive correlations were found between MPV and varicocele grade as between MPV and diameter of left spermatic vein (P < .05).
Conclusion: The increase in MPV is independent of the disease, and the increase in varicocele grade is associated with higher MPV in varicocele patients. On the basis of the importance of the vascular component in the pathophysiology of varicocele, we would suggest conducting more studies with platelets in varicocele patients.
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| http://dx.doi.org/10.1016/j.urology.2012.01.019 | DOI Listing |
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