This paper describes the recent progresses concerning the on-line ion source at the Tri University Meson Factory/Isotope Separator and ACcelerator (TRIUMF/ISAC) Radioactive Ion-Beam Facility; description of the new design of the surface-ion-source for improved stability of the beam intensity, description of the transport path to the east target station at ISAC, description of the new brazing techniques that solved recurrent problems with water leaks on the target/ion source assembly in the vacuum system, finally, recent developments concerning the Forced Electron Beam Induced Arc Discharge (FEBIAD) ion source are reported. In particular, a study on the effect of the plasma chamber volume on the ionization efficiency was completed.
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http://dx.doi.org/10.1063/1.3678652 | DOI Listing |
BMC Complement Med Ther
January 2025
Department of Chinese Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, 11490, Taiwan.
Background: Demonstrating a positive impact of educational programs on clinical care outcomes is challenging. We assess students' knowledge, attitudes, and behaviors as short-term outcomes of integrating a structured Traditional Chinese Medicine course within a Western medical school.
Methods: A prospective questionnaire survey was conducted among first-year and second-year undergraduate medical students who participated in the "Introduction to Chinese Medicine" course in 2020.
Brain
January 2025
Department of Neurology, University of South Carolina, Columbia, SC 29203, USA.
Despite decades of advancements in diagnostic MRI, 30-50% of temporal lobe epilepsy (TLE) patients remain categorized as "non-lesional" (i.e., MRI negative or MRI-) based on visual assessment by human experts.
View Article and Find Full Text PDFEnviron Res
January 2025
Missouri Breaks Industries Research Inc, Eagle Butte, SD; Department of Pathology, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, ND.
Introduction: Selenium (Se), a trace element found in soil and groundwater, is necessary for many biological functions, including cerebrovascular health, through selenoprotein formation. However, high concentrations may be harmful. American Indians face elevated cerebrovascular disease rates, which may be associated with other trace elements, such as Se.
View Article and Find Full Text PDFPlant Physiol Biochem
January 2025
All India Network Project on Soil Biodiversity-Biofertilizers, ICAR-Indian Institute of Soil Science, Bhopal, 462038, India.
This study evaluated a dual management approach to enhance plant-growth by improving soil fertility, reducing pathogenic stress using PGPR that affect phosphorus-transporter (pht) genes. Among 213 maize rhizobacterial isolates, 40 demonstrated the ability to solubilize tri-calcium phosphate, potassium, zinc, and silicon, showing various PGP traits. Nine of these isolates exhibited significant antagonistic activity against the plant pathogens Colletotrichum chlorophyti and Xanthomonas axonopodis.
View Article and Find Full Text PDFSci Adv
January 2025
Molecular Pharmacology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
A major limiting factor in the success of chimeric antigen receptor (CAR) T cell therapy for the treatment of solid tumors is targeting tumor antigens also found on normal tissues. CAR T cells against GD2 induced rapid, fatal neurotoxicity because of CAR recognition of GD2 normal mouse brain tissue. To improve the selectivity of the CAR T cell, we engineered a synthetic Notch receptor that selectively expresses the CAR upon binding to P-selectin, a cell adhesion protein overexpressed in tumor neovasculature.
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