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SARS-CoV-2 excretion and genetic evolution in nasopharyngeal and stool samples from primary immunodeficiency and immunocompetent pediatric patients.
Virol J
January 2025
Laboratory of Clinical Virology, WHO Regional Reference Laboratory for Poliomyelitis and Measles for in the Eastern Mediterranean Region, Institut Pasteur de Tunis, University of Tunis El Manar, 13 place Pasteur, BP74 1002 le Belvédère, Tunis, Tunisia.
Background: Primary Immunodeficiency disorders (PID) can increase the risk of severe COVID-19 and prolonged infection. This study investigates the duration of SARS-CoV-2 excretion and the genetic evolution of the virus in pediatric PID patients as compared to immunocompetent (IC) patients.
Materials And Methods: A total of 40 nasopharyngeal and 24 stool samples were obtained from five PID and ten IC children.
Trend and forecast of measles disease, in East Gojjam Zone, Amhara Region, Northwest Ethiopia, 2023: a crossectional study.
BMC Res Notes
December 2024
Department of Statistics, College of Natural and Computational Sciences, Gambella University, Gambella, Ethiopia.
Background: Measles is a very contagious illness that can be clinically diagnosed and intervened quickly. It is caused by the measles virus Morbillivirus. The disease has a case fatality rate of 5% to 10% in the sub-Saharan region.
View Article and Find Full Text PDFCoverage of Second Dose of Measles-Containing Vaccine (MCV-2) and Japanese Encephalitis Vaccine (JE-2) and Its Predictors Among Children 2-5 Years Old in the Ormanjhi Block of Ranchi, Jharkhand, India: A Mixed Method Study.
Cureus
November 2024
Department of Community Medicine/Preventive and Social Medicine, Rajendra Institute of Medical Sciences, Ranchi, IND.
Introduction Administering the measles vaccine at an appropriate age and dosage in children is important for India to eliminate measles, a potentially deadly vaccine-preventable disease. Similarly, the Japanese encephalitis (JE) vaccine, particularly in endemic regions is important to prevent morbidity and high-case fatality from the disease. The study attempts to evaluate the coverage of measles and JE vaccines and their predictors.
View Article and Find Full Text PDFSubstantial Improvement in a Patient with Subacute Sclerosing Panencephalitis: An Unusual Case Report.
Tremor Other Hyperkinet Mov (N Y)
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Department of Neurology, King George's Medical University, Lucknow, India.
Background: Subacute Sclerosing Panencephalitis (SSPE) is a fatal disorder marked by gradual cognitive and motor deterioration, leading to death typically within 1-3 years.
Case Report: A 20-year-old woman with progressive abnormal behaviour, forgetfulness, and involuntary movements showed significant improvement after treatment with interferon and isoprinosine. Initially severely cognitively impaired and dependent, she regained independence and demonstrated marked cognitive enhancement, her MMSE improved from 15 to 28 and reduced myoclonus.
Inequalities in measles immunization coverage among two-year-olds in Sierra Leone, 2008-2019.
BMC Infect Dis
November 2024
REMS Consultancy Services, Takoradi, Sekondi-Takoradi, Ghana.
Background: Measles, a highly contagious and potentially fatal disease, remains a significant public health concern, particularly in low- and middle-income countries. Vaccination is the most effective way to prevent measles and achieving high immunization coverage is crucial for protecting children and communities. This study investigated the trends and inequalities in measles immunization coverage among two-year-olds in Sierra Leone between 2008 and 2019.
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