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Dental findings and oral health status in patients with mucopolysaccharidosis: a case series. | LitMetric

AI Article Synopsis

  • This study investigates the oral health and manifestations in a group of patients with mucopolysaccharidosis (MPS), a genetic disorder that affects the body's ability to break down certain sugars.
  • A total of 12 patients, aged 3 to 31, were examined, revealing high rates of dental caries, periodontal issues, and specific oral abnormalities like delayed tooth eruption and thickening of oral structures.
  • The findings highlight the need for awareness and education regarding the unique dental challenges faced by MPS patients, which could aid in accurate diagnosis and early treatment.

Article Abstract

Objective: To present a mucopolysaccharidosis (MPS) case series evaluating oral manifestations (clinical and radiographic), oral health status and discussing its implications.

Patients And Methods: All patients with MPS attending the Genetics clinic/Brazil were evaluated by means of anamnesis, clinical and radiographic examinations.

Results: The final sample consisted of 12 subjects (nine males and three females), with ages ranging from 3-31 years old. Concerning oral health, it was observed high levels of caries and periodontal problems. About oral manifestations, this study clinically observed more cases of delayed tooth eruption, thickness of alveolar process and thick lips. Radiographically, it was observed alterations on condyle, mandibular ramus and joint fossa.

Conclusion: The dental changes in MPS population are high and consequently it is important to know them for differential diagnoses, early treatment intervention, prevention and education of both patients and parents/caregivers about oral health.

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Source
http://dx.doi.org/10.3109/00016357.2011.654255DOI Listing

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