Abomasal hypomotility is a prerequisite for abomasal displacement in cattle and is present immediately after surgical correction of left displaced abomasum or abomasal volvulus. Hypocalcemia, hypokalemia, and hyperinsulinemia should be corrected in cattle suspected to have abomasal hypomotility. The most effective prokinetic for calves and adult cattle suspected to have abomasal hypomotility is erythromycin.
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http://dx.doi.org/10.1016/j.cvfa.2011.12.008 | DOI Listing |
Res Vet Sci
January 2021
Division of Nuclear Medicine, Department of Radiology, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Abomasal hypomotility is one of the important causes of neonatal mortality in small ruminants. Various pharmaceutical agents have been studied to address this problem in large ruminants. The aim of this study was to determine the effect of parenteral administration of tylosin and ivermectin on abomasal emptying rate in neonatal suckling lambs.
View Article and Find Full Text PDFJ Vet Pharmacol Ther
April 2018
Division of Pharmacology and Toxicology, Department of Preclinical Sciences, Faculty of Veterinary Medicine, Warsaw University of Life Sciences, Warsaw, Poland.
Continued ingestion of plant secondary metabolites by ruminants can provoke pharmacological interactions with pharmaceutical agents used in animals. As some drugs and phytocompounds affect smooth muscle activity, the aim of this study was to verify the possible interaction between selected pharmaceutical agents and plant secondary metabolites towards bovine gastrointestinal motility. The interactions between phytocompounds-apigenin, quercetin, hederagenin, medicagenic acid-and medicines-erythromycin, flunixin meglumine and levamisole-were evaluated on bovine isolated abomasal and duodenal specimens obtained from routinely slaughtered cows.
View Article and Find Full Text PDFVet Res Forum
June 2017
Department of Internal Medicine and Clinical Pathology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.
Displacement of the abomasum is a common disease of the gastrointestinal tract in dairy cattle. Abomasal displacement has been associated with abomasal hypomotility. Therefore, it is necessary to identify effective therapeutic agents that stimulate abomasal motility in cattle.
View Article and Find Full Text PDFCan J Vet Res
January 2014
Department of Clinical Sciences, College of Veterinary Medicine, Shahid Chamran University, Ahvaz, Iran (Rashnavadi, Nouri, Haji Hajikolaei); Department of Basic Sciences, College of Veterinary Medicine, Shahid Chamran University, Ahvaz Iran (Najafzadeh); and Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Purdue University, West Lafayette, Indiana, USA (Constable).
Impaired abomasal motility is common in cattle with abomasal disorders. The macrolide erythromycin has been demonstrated to be an effective prokinetic agent in healthy calves and in adult cattle with abomasal volvulus or left displaced abomasum. We hypothesized that 2 structurally related macrolides, spiramycin and tulathromycin, would also be effective prokinetic agents in cattle.
View Article and Find Full Text PDFVet Clin North Am Food Anim Pract
March 2012
Department of Veterinary Clinical Sciences, Purdue University, 625 Harrison Street, West Lafayette, IN 47905-2026, USA.
Abomasal hypomotility is a prerequisite for abomasal displacement in cattle and is present immediately after surgical correction of left displaced abomasum or abomasal volvulus. Hypocalcemia, hypokalemia, and hyperinsulinemia should be corrected in cattle suspected to have abomasal hypomotility. The most effective prokinetic for calves and adult cattle suspected to have abomasal hypomotility is erythromycin.
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