Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.4321/s1130-01082012000200007 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Developing a knowledge transfer and exchange strategy for a clinical trials unit.
Trials
January 2025
MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, UCL, 90 High Holborn, London, WC1V 6LJ, UK.
Need For A Strategic Approach To Knowledge Transfer And Exchange: Late-phase clinical trials and systematic reviews find results that have the potential to improve health outcomes for people. However, there are often delays in these results influencing clinical practice. We developed a knowledge transfer and exchange strategy to support research teams, aiming to identify activities along the research process to maximise and accelerate the research impact.
View Article and Find Full Text PDFA machine learning-based model to predict POD24 in follicular lymphoma: a study by the Chinese workshop on follicular lymphoma.
Biomark Res
January 2025
Department of Hematology, The First Affiliated Hospital of Xiamen University and Institute of Hematology, School of Medicine, Xiamen University, Xiamen, 361003, P.R. China.
Background: Disease progression within 24 months (POD24) significantly impacts overall survival (OS) in patients with follicular lymphoma (FL). This study aimed to develop a robust predictive model, FLIPI-C, using a machine learning approach to identify FL patients at high risk of POD24.
Methods: A cohort of 1,938 FL patients (FL1-3a) from seventeen centers nationwide in China was randomly divided into training and internal validation sets (2:1 ratio).
How do lesions affect limb lengthening in children with Ollier's disease?
BMC Musculoskelet Disord
January 2025
Department of Pediatric Orthopaedics, Children's Hospital of Fudan University, National Children's Medical Center, 399 Wanyuan Rd, Minhang District, Shanghai, 201102, China.
Purpose: Ollier's disease (multiple enchondromatosis) can cause severe lower limb length discrepancy and deformity in children. Osteotomy and limb lengthening with external fixation can correct the lower extremity deformity. There may be lesions in the osteotomy part (OP), and the internal fixation part of the external fixation(FP).
View Article and Find Full Text PDFMachine learning based identification of an amino acid metabolism related signature for predicting prognosis and immune microenvironment in pancreatic cancer.
BMC Cancer
January 2025
Department of General Surgery, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Peking, Beijing, 100023, People's Republic of China.
Background: Pancreatic cancer is a highly aggressive neoplasm characterized by poor diagnosis. Amino acids play a prominent role in the occurrence and progression of pancreatic cancer as essential building blocks for protein synthesis and key regulators of cellular metabolism. Understanding the interplay between pancreatic cancer and amino acid metabolism offers potential avenues for improving patient clinical outcomes.
View Article and Find Full Text PDFPredicting the Invasiveness of Mixed Ground-Glass Nodules Based on Spectral Computed Tomography-Derived Parameters and Tumor Abnormal Protein Levels: Development and Validation of a Model.
Acad Radiol
January 2025
Department of Radiology, Shengjing Hospital of China Medical University, China (Y.Y., T.W.). Electronic address:
Rationale And Objectives: Mixed ground-glass nodules (mGGNs) are highly malignant and common nonspecific lung imaging findings. This study aimed to explore whether combining quantitative and qualitative spectral dual-layer detector-based computed tomography (SDCT)-derived parameters with serological tumor abnormal proteins (TAPs) and thymidine kinase 1 (TK1) expression enhances invasive mGGN diagnostic efficacy and to develop a joint diagnostic model.
Materials And Methods: This prospective study included patients with mGGNs undergoing preoperative triple-phase contrast-enhanced SDCT with TAP and TK1 tests.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!