This special issue presents research concerning multistable perception in different sensory modalities. Multistability occurs when a single physical stimulus produces alternations between different subjective percepts. Multistability was first described for vision, where it occurs, for example, when different stimuli are presented to the two eyes or for certain ambiguous figures. It has since been described for other sensory modalities, including audition, touch and olfaction. The key features of multistability are: (i) stimuli have more than one plausible perceptual organization; (ii) these organizations are not compatible with each other. We argue here that most if not all cases of multistability are based on competition in selecting and binding stimulus information. Binding refers to the process whereby the different attributes of objects in the environment, as represented in the sensory array, are bound together within our perceptual systems, to provide a coherent interpretation of the world around us. We argue that multistability can be used as a method for studying binding processes within and across sensory modalities. We emphasize this theme while presenting an outline of the papers in this issue. We end with some thoughts about open directions and avenues for further research.
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http://dx.doi.org/10.1098/rstb.2011.0254 | DOI Listing |
Nat Commun
December 2024
The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Deafness is the most common form of sensory impairment in humans and frequently caused by defects in hair cells of the inner ear. Here we demonstrate that in male mice which model recessive non-syndromic deafness (DFNB6), inactivation of Tmie in hair cells disrupts gene expression in the neurons that innervate them. This includes genes regulating axonal pathfinding and synaptogenesis, two processes that are disrupted in the inner ear of the mutant mice.
View Article and Find Full Text PDFFront Psychol
December 2024
Departamento de Psicologia, Laboratório de Neurociência do Comportamento, Pontifícia Universidade Católica do Rio de Janeiro, Rio de Janeiro, Brazil.
To form a unified and coherent perception of the organism's state and its relationship with the surrounding environment, the nervous system combines information from various sensory modalities through multisensory integration processes. Occasionally, data from two or more sensory channels may provide conflicting information. This is particularly evident in experiments using the mirror-guided drawing task and the mirror-box illusion, where there is conflict between positional estimates guided by vision and proprioception.
View Article and Find Full Text PDFBrain Behav Immun
December 2024
Wolfson Sensory, Pain and Regeneration Centre, King's College London, Guy's Campus, London Bridge, London SE1 1UL, UK. Electronic address:
Angiotensin II is well known to have an important influence on blood pressure, mediated via the angiotensin II type 1 receptor (AT1R), and more recent studies have shown that angiotensin II may play an important additional role in eliciting pain via a distinct action at the angiotensin II type 2 receptor (AT2R). Signalling pathways that link activation of AT2R to a sensation of pain are, however, incompletely understood. Here we use rodent inflammatory pain models to confirm that selective activation of AT2R triggers aversive responses, and that these are abolished by either antagonism or genetic deletion of AT2R.
View Article and Find Full Text PDFSci Rep
December 2024
Department of Zoology, University of São Paulo, São Paulo, SP, Brazil.
Animals have evolved numerous mechanisms to perceive and interact with the environment that can be translated into different sensory modalities. However, the genomic and phenotypic features that support sensory functions remain enigmatic for many invertebrates, such as bivalves, an ecologically and economically important taxonomic group. No repertoire of sensory genes has been characterized in bivalves, representing a significant knowledge gap in molluscan sensory biology.
View Article and Find Full Text PDFSci Rep
December 2024
Department of Communication Sciences and Disorders, Faculty of Social Welfare and Health Sciences, University of Haifa, Haifa, Israel.
Age-related sensory declines are unavoidable and closely linked to decreased visual, auditory, and cognitive functions. However, the interrelations of these declines remain poorly understood. Despite extensive studies in each domain, shared age-related characteristics are complex and may not consistently manifest direct relationships at the individual level.
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