Numerous animal experiments and human studies have shown that intermittent injection of parathyroid hormone (PTH) exerts anabolic effects by increasing bone mass, whereas continuous PTH treatment decreases the bone mass. Thus, PTH has diverse effects on bone metabolism depending on the mode of administration. Several reports suggested that the duration of the serum concentration of PTH above the baseline level of endogenous PTH is a critical factor in regulating such anabolic and catabolic actions on the bone mass. However, the molecular mechanism of different PTH actions is not fully understood yet.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Extramedullary plasmacytoma with the uvula as first affected site: A case report.
World J Clin Oncol
January 2025
Department of Hematology, The First Affiliated Hospital of Jishou University, Jishou 416000, Hunan Province, China.
Background: Extramedullary plasmacytoma (EMP) represents one of the rarer forms of plasma cell malignancies, capable of impacting a variety of tissues and organs throughout the body. The majority of EMP cases are predominantly found in the head and neck region, especially within the laryngopharynx, as well as in the gastrointestinal tract. While there have been documented instances of oropharyngeal involvement in EMP cases in the academic literature, it is important to note that EMP specifically affecting the uvula is exceedingly uncommon.
View Article and Find Full Text PDFThe association between dietary omega-3 intake and osteoporosis: a NHANES cross-sectional study.
Front Nutr
January 2025
The Third Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, China.
Background: Recent research suggests that omega-3 fatty acids may play a role in bone metabolism through their influence on bone mineral density (BMD) and the regulation of bone turnover markers. However, epidemiological evidence linking omega-3 intake to the risk of developing osteoporosis is still emerging and remains inconclusive. This study aims to clarify the role of dietary omega-3 fatty acids in the prevention of osteoporosis.
View Article and Find Full Text PDFTumor-Induced Osteomalacia Localized by Systemic Venous Sampling and Ga-DOTATOC Positron Emission Tomography.
JCEM Case Rep
February 2025
First Department of Internal Medicine, Wakayama Medical University, Wakayama City, Wakayama 641-8509, Japan.
Tumor-induced osteomalacia is characterized by hypophosphatemia and fragility fractures caused by fibroblast growth factor 23 (FGF23)-producing tumors. We report a case of tumor-induced osteomalacia in which the tumor location could be determined by gallium 68 (Ga)-DOTATOC positron emission tomography (PET)/computed tomography (CT). A 74-year-old woman had recurrent fractures and bone pain.
View Article and Find Full Text PDFPARATHYROID CARCINOMA: ULTRASONOGRAPHIC AND CLINICAL EXPERIENCE.
Acta Clin Croat
December 2023
Clinical Department of Nuclear Medicine and Radiation Protection, Zagreb University Hospital Center, Zagreb, Croatia.
Parathyroid cancer is an extremely rare malignancy that usually leads to hyperparathyroidism. The aim of this report is to present clinical and ultrasonographic features of tumors in six patients (5 females; mean age 53.2 years) treated for parathyroid carcinoma at the Department of Nuclear Medicine during 20 years.
View Article and Find Full Text PDFThe association between dietary inflammatory index and bone health in US adolescents: Analysis of the NHANES data.
Bone Rep
March 2025
Department of pediatrics, Liaocheng Second People's Hospital, Liaocheng 252600, China.
Introduction: Adolescents with a lower peak bone mineral density (BMD) and bone mineral content (BMC) have an elevated risk of osteoporosis in adulthood. The impact of diet on bone health, particularly its role in managing inflammation, which is a key factor in bone health, is gaining wider recognition. Despite evidence that anti-inflammatory diets can enhance bone health, the link between the dietary inflammatory index (DII) and bone health among US adolescents has not been thoroughly investigated.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!