Enantioselective synthesis of Garner's aldehyde by asymmetric hydroformylation.

J Org Chem

Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, Wisconsin 53706-1322, USA.

Published: March 2012

AI Article Synopsis

  • Garner's aldehyde consists of two enantiomers that can be produced from the same starting material.
  • The method used to create these enantiomers is called catalytic asymmetric hydroformylation.
  • This process involves adding a formyl group to an alkene (specifically alkene 4) to yield different chiral forms of the aldehyde.

Article Abstract

Both enantiomers of Garner's aldehyde (3) are prepared from the same alkene 4 by catalytic asymmetric hydroformylation.

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Source
http://dx.doi.org/10.1021/jo300025tDOI Listing

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