In this study, we examined the biofilm forming ability, the mRNA expression of curli genes and the morphologies of curli fimbriae and biofilms in clinical isolates of Enterobacter cloacae. The csgBA operon was found in 11 (78.6%) of the 14 isolates. The ability of E. cloacae isolates to form biofilms was significantly correlated with the mRNA expression level of the csgA and csgD genes. The curli protein fimbriae appeared as tangled fibers and the curli-proficient strain formed mature biofilms. Our data suggest that the expression of the curli fimbriae play an important role in biofilm formation in E. cloacae.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s12275-012-2044-2 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Functional role of the biofilm regulator CsgD in sv. Typhi.
Front Cell Infect Microbiol
December 2024
Center for Microbial Pathogenesis, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, United States.
Introduction: Typhoid fever is an infectious disease primarily caused by sv. Typhi ( Typhi), a bacterium that causes as many as 20 million infections and 600,000 deaths annually. Asymptomatic chronic carriers of S.
View Article and Find Full Text PDFCommercial Day-Old Chicks in Nigeria Are Potential Reservoirs of Colistin- and Tigecycline-Resistant Potentially Pathogenic .
Antibiotics (Basel)
November 2024
Department of Livestock and Pasture Science, University of Fort Hare, Alice 5700, South Africa.
Frequent use of colistin (COL) and tetracyclines in the Nigerian poultry sector potentially triggers bacterial resistance against COL and tigecycline (TIG), which are last-line antibiotics used to treat multidrug-resistant infections. This study aimed to isolate COL- and TIG-resistant . from commercial day-old chicks distributed to poultry farmers in Nsukka Southeastern Nigeria, assess the production of extended-spectrum β-lactamase (ESBL) and carbapenemase by the isolates, and establish their pathogenic potentials.
View Article and Find Full Text PDFRoles of Response Regulators in the Two-Component System in the Formation of Stress Tolerance, Motility and Biofilm in Enteritidis.
Foods
November 2024
MOST-USDA Joint Research Center for Food Safety, State Key Laboratory of Microbial Metabolism, School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai 200240, China.
Two-component systems (TCS) of serovar Enteritidis are composed of a histidine kinase and a response regulator (RR) and represent a critical mechanism by which bacteria develop resistance to environmental stress. Here, we characterized the functions of RRs in TCS in the formation of stress tolerance, motility and biofilm using twenty-six . Enteritidis RR-encoding gene deletion mutants.
View Article and Find Full Text PDFEpigallocatechin gallate protects mice from ser. Typhimurium infection by modulating bacterial virulence through quorum sensing inhibition.
Front Cell Infect Microbiol
October 2024
Animal Experiment Center, Sichuan Academy of Chinese Medicine Sciences, Chengdu, China.
Article Synopsis
- Typhimurium is a significant pathogen linked to serious gastrointestinal diseases and foodborne illnesses, regulated by quorum sensing and the type III secretion system.* -
- The study showed that epigallocatechin gallate (EGCG), a compound in green tea, reduces Typhimurium's virulence by inhibiting factors like autoinducers, biofilm formation, and flagellar activity.* -
- In mouse models, EGCG effectively decreased intestinal colonization by Typhimurium and lessened intestinal damage, highlighting its potential as a treatment for Typhimurium infections.*
Profiling the Enterobacterales Community Isolated from Retail Foods in England.
J Food Prot
November 2024
Department of Applied Sciences, Northumbria University, Newcastle upon Tyne NE1 8ST, United Kingdom. Electronic address:
Enterobacterales include foodborne pathogens of importance to public health and are often targeted in food surveillance programs as both safety and hygiene indicators. Furthermore, Enterobacterales are important in the context of antimicrobial resistance dissemination, also impacting infection treatment efficacy. In this study, the prevalence and characteristics of Enterobacterales in UK retail foods were examined.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!