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Chapter 6: SYNDROMIC PRIMARY HYPERPARATHYROIDISM.
Ann Endocrinol (Paris)
January 2025
Endocrinology Department, Huriez Hospital, Lille University Hospital, France. Electronic address:
Syndromic primary hyperparathyroidism has several features in common: younger age at diagnosis when compared with sporadic primary hyperparathyroidism, often synchronous or metachronous multi-glandular involvement, higher possibility of recurrence, association with other endocrine or extra-endocrine disorders, and suggestive family background with autosomal dominant inheritance. Hyperparathyroidism in multiple endocrine neoplasia type 1 is the most common syndromic hyperparathyroidism. It is often asymptomatic in adolescents and young adults, but may be responsible for recurrent lithiasis and/or bone loss.
View Article and Find Full Text PDFUndifferentiated Pleomorphic Sarcoma of the Proximal Thigh With Neoplastic Fever and Metachronous Sternal Metastases: A Case Report and Review of the Literature.
Cureus
October 2024
Department of Medicine, Universidad Nacional Autónoma de Honduras, Tegucigalpa, HND.
Article Synopsis
- * Neoplastic fever (NF) is a rare fever associated with malignant tumors, and in this case, it presented in an unusual manner in a patient with UPS who had refractory fever and systemic inflammation.
- * A 58-year-old male patient with UPS-NF had a history of fever of unknown origin and was treated with chemotherapy and surgery, but ultimately experienced poor outcomes, including metastasis and additional paraneoplastic symptoms.
Imaging of Upper Tract Urothelial Carcinoma.
Radiographics
November 2024
From the Department of Radiology, Mayo Clinic, 200 1st St SW, Rochester, MN 55905 (H.N., H.T., N.T.); and Departments of Radiology (C.V.W., A.K.) and Laboratory Medicine and Pathology (M.L.S.), Mayo Clinic, Scottsdale, Ariz.
Upper tract urothelial carcinoma (UTUC) originates in the renal pelvis or ureters and typically affects elderly patients, with its incidence increasing over the past few decades. UTUC is a distinct clinical entity with more aggressive clinical behavior than that of lower tract urothelial carcinoma. Due to the significant challenge of acquiring an adequate tissue sample for biopsy, comprehensive risk stratification is required for treatment planning, including radical nephroureterectomy and kidney-sparing management.
View Article and Find Full Text PDFKüttner's Tumor and Autoimmune Pancreatitis as Metachronous Manifestations of IgG4-Related Disease.
J Investig Med High Impact Case Rep
October 2024
St. Joseph's University Medical Center, Paterson, NJ, USA.
Article Synopsis
- Immunoglobulin G4-related disease (IgG4-RD) is a condition affecting multiple organs, characterized by painless swelling and inflammation, with common sites being the pancreas and salivary glands.
- Diagnosis involves various tests (serological, imaging, histopathological) and primary treatment is with glucocorticoids, which often yields good results.
- A case study highlights a geriatric male incorrectly suspected of pancreatic cancer, who was found to have autoimmune pancreatitis, a type of IgG4-RD, and responded well to steroid treatment.
An Ode to the Heart from Down Under!
Indian J Surg Oncol
September 2024
Department of Medical Oncology, R.L. Jalappa Institute of Oncology, Sri Devaraj Urs Academy of Higher Education and Research, Tamaka, Kolar, Karnataka India.
Article Synopsis
- Testicular cancers, like embryonal cell carcinoma, rarely spread to the heart, but when they do, it usually indicates widespread disease.
- A 28-year-old man experienced cardiac metastasis from his testicular cancer, but his symptoms improved following chemotherapy.
- It's crucial for healthcare providers to maintain a high suspicion for heart issues in patients with chest symptoms and to involve cardiologists early for better treatment outcomes.
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