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Pathogen genomic surveillance and the AI revolution.
J Virol
January 2025
MRC-University of Glasgow Centre for Virus Research, Glasgow, Scotland, United Kingdom.
The unprecedented sequencing efforts during the COVID-19 pandemic paved the way for genomic surveillance to become a powerful tool for monitoring the evolution of circulating viruses. Herein, we discuss how a state-of-the-art artificial intelligence approach called protein language models (pLMs) can be used for effectively analyzing pathogen genomic data. We highlight examples of pLMs applied to predicting viral properties and evolution and lay out a framework for integrating pLMs into genomic surveillance pipelines.
View Article and Find Full Text PDFThe Genomics Revolution Drives a New Era in Entomology.
Annu Rev Entomol
January 2025
Department of Entomology, China Agricultural University, Beijing, China; email:
Thanks to the fast development of sequencing techniques and bioinformatics tools, sequencing the genome of an insect species for specific research purposes has become an increasingly popular practice. Insect genomes not only provide sets of gene sequences but also represent a change in focus from reductionism to systemic biology in the field of entomology. Using insect genomes, researchers are able to identify and study the functions of all members of a gene family, pathway, or gene network associated with a trait of interest.
View Article and Find Full Text PDFDeltopectoral approach without subscapularis detachment for reverse shoulder arthroplasty. Technique and results of a safe and reproducible subscapularis-sparing approach.
JSES Rev Rep Tech
February 2025
Clinique Claude Bernard, Unité de Chirurgie Orthopédique, Metz, France.
Background: The importance of the subscapularis for reverse total shoulder arthroplasty has been demonstrated, especially for internal rotation and stability. In a deltopectoral approach, a detachment of the subscapularis is performed (tenotomy, tuberosity peeling, or osteotomy), but the tendon is not always repairable at the end. When it is repaired, healing is obtained in only 40%-76% of the cases, with potential consequences for the outcomes.
View Article and Find Full Text PDF[The role of volatile organic compounds in plant-insect communication].
Biol Aujourdhui
January 2025
Sorbonne Université, Institut d'Écologie et des Sciences de l'Environnement de Paris, 4 place Jussieu, 75005 Paris, France - Institut Universitaire de France, Paris, France.
Insects and flowering plants are the most abundant and diverse multicellular organisms on Earth, accounting for 75% of known species. Their evolution has been largely interdependent since the so-called Angiosperm Terrestrial Revolution (100-50 Mya), when the explosion of plant diversity stimulated the evolution of pollinating and herbivorous insects. Plant-insect interactions rely heavily on chemical communication via volatile organic compounds (VOCs).
View Article and Find Full Text PDFThe Kerbernez long-term experiment: A dataset on crop yield and soil organic matter evolution in forage crop rotations and permanent grasslands in a temperate oceanic climate.
Data Brief
February 2025
UMR SAS, INRAE, Institut Agro, 35 000 Rennes, France.
Forage crop rotations including grasslands, common in dairy systems, are known to ensure good productivity and limit the decrease of soil organic matter frequently observed in permanent arable land. A dataset was built to compile data from the Kerbernez long-term experiment, conducted in Brittany(France) from 1978 to 2005. This experiment compared the effect of different forage crop rotations fertilized with ammonium nitrate and/or slurry, with or without grassland, on forage production (quantity, quality) and changes in soil physio-chemical characteristics.
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