Introduction: Cutaneous manifestations in patients with acute leukemia (AL) cover a broad spectrum, including those due to leukemia per se, to chemotherapy and other drugs and those inherent to hospital care.
Material And Methods: This is a cohort study in a tertiary hospital setting where the development of dermatoses was followed for 2 years in 22 patients with the diagnosis of AL.
Results: During the study, all patients developed some type of dermatosis, mostly due to chemotherapy.
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J Neuroophthalmol
October 2024
University of Pennsylvania Perelman School of Medicine (SP); Penn Presbyterian Medical Center (SP), Philadelphia, Pennsylvania; John F. Hardesty, MD Department of Ophthalmology and Visual Sciences (LS, GVS), Washington University in St. Louis School of Medicine, St. Louis, Missouri; and Weill Cornell Medical College (AGL), Houston Methodist, Houston, Texas.
Probl Radiac Med Radiobiol
December 2024
Bogomolets National Medical University, Taras Shevchenko Blvd, 13, Kyiv, 01024, Ukraine.
The review presents literature data on the role of the ТР53 gene and ionizing radiation (IR) in the pathogenesis of acute myeloid leukemia (AML).The violation of ТР53 functioning as a promoter of AML induction under the influence of negative external factors (IR, chemotherapeutic agents) was analyzed. New directions of AML stratification are presented, which will allow to optimize the future therapy and extend the life expectancy of this category of patients.
View Article and Find Full Text PDFInt Urol Nephrol
December 2024
Department of Pediatrics, The First Affiliated Hospital of Henan University of Traditional Chinese Medicine, Zhengzhou, 450000, China.
Purpose: Henoch-Schönlein purpura nephritis (HSPN) has a poor prognosis and variable pathophysiology. The present study aimed to analyze the kidney injury, clinicopathology, and prognosis of HSPN children.
Methods: This retrospective study examined 249 children with HSPN.
Neurosurg Rev
December 2024
Trauma Research Center, Shahid Rajaee (Emtiaz) Trauma Hospital, Chamran Blvd, Shiraz, 7194815711, Iran.
Background: Traumatic Brain Injury (TBI) is a leading cause of hospitalization and disability in young and middle-aged adults. This study aims to survey the efficacy of oral modafinil, a low-side-effect central nervous system stimulant, in the enhancement of consciousness recovery in moderate to severe TBI patients in the ICUs of a referral trauma center.
Materials And Methods: All ICU patients meeting inclusion criteria between April 2021 and April 2023 were screened.
JAMA Netw Open
December 2024
Center for Health Equity Research and Promotion, VA Pittsburgh Healthcare System, Pittsburgh, Pennsylvania.
Importance: The Veterans Health Administration (VHA) reports multiple indicators of hospital surgical performance, including hospital risk-standardized 30-day readmission rates (RSRRs). Currently, most routinely reported measures do not include readmissions that occur outside VHA hospitals. The impact of readmissions outside the VHA on hospital RSRR is not known.
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