Severity: Warning
Message: Undefined array key "choices"
Filename: controllers/Detail.php
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File: /var/www/html/application/controllers/Detail.php
Line: 249
Function: _error_handler
File: /var/www/html/index.php
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Function: require_once
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Message: Trying to access array offset on value of type null
Filename: controllers/Detail.php
Line Number: 249
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File: /var/www/html/application/controllers/Detail.php
Line: 249
Function: _error_handler
File: /var/www/html/index.php
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Message: Trying to access array offset on value of type null
Filename: controllers/Detail.php
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File: /var/www/html/application/controllers/Detail.php
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Function: _error_handler
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Message: Trying to access array offset on value of type null
Filename: controllers/Detail.php
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Filename: models/Detail_model.php
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Function: strpos
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Function: insertAPISummary
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Filename: controllers/Detail.php
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Filename: controllers/Detail.php
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Some people conform more than others. Across different contexts, this tendency is a fairly stable trait . This stability suggests that the tendency to conform might have an anatomical correlate . Values that one associates with available options, from foods to political candidates, help to guide choices and behaviour. These values can often be updated by the expressed preferences of other people as much as by independent experience. In this correspondence, we report a linear relationship between grey matter volume (GM) in a region of lateral orbitofrontal cortex (lOFC) and the tendency to shift reported desire for objects toward values expressed by other people. This effect was found in precisely the same region in each brain hemisphere. lOFC also predicted the functional hemodynamic response in the middle frontal gyrus to discovering that someone else's values contrast with one's own. These findings indicate that the tendency to conform one's values to those expressed by other people has an anatomical correlate in the human brain.
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http://dx.doi.org/10.1016/j.cub.2012.01.012 | DOI Listing |
J ECT
December 2024
From the Department of Psychiatry, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Objectives: We studied the acceptability, feasibility, tolerability, and preliminary effectiveness of combined cue exposure and anodal high-definition transcranial direct current stimulation (HD-tDCS) on the right dorsolateral prefrontal cortex (DLPFC) on cannabis craving in cannabis use disorder (CUD).
Methods: We randomly assigned 48 participants equally in 4 groups: A, tDCS and cannabis cue exposure; B, tDCS and neutral image; C, sham tDCS and cue exposure; and D, sham tDCS and neutral image. The images were validated by Delphi consensus.
Behav Pharmacol
December 2024
Department of Pharmacology, Center of Excellence for Pharmaceutical Sciences, North-West University, Potchefstroom, South Africa.
Traumatic stress exposure increases noradrenaline (NA) release, which contributes to anxiety and impaired risk-appraisal. Guanfacine, a selective alpha-2A adrenergic receptor agonist, has been used to treat stress-related disorders characterised by impaired prefrontal cortex function. By acting on both presynaptic inhibitory autoreceptors and postsynaptic heteroreceptors, guanfacine attenuates stress reactivity and enhances cognition.
View Article and Find Full Text PDFBehav Pharmacol
December 2024
Neurolixis SAS, Castres, France.
Ketamine displays efficacious rapid-acting antidepressant (RAAD) activity in the rat chronic mild stress (CMS) model. It rapidly reverses anhedonia (CMS-induced sucrose consumption deficit) and attenuates working memory deficit (novel object recognition: NOR) following both systemic (intraperitoneal, i.p.
View Article and Find Full Text PDFFront Neurosci
December 2024
Intramural Research Program, National Institute on Drug Abuse National Institutes of Health, Baltimore, MD, United States.
Miniature fluorescence microscopes (miniscopes) are one of the most powerful and versatile tools for recording large scale neural activity in freely moving rodents with single cell resolution. Recent advances in the design of genetically encoded calcium indicators (GECIs) allow to target distinct neuronal populations with non-overlapping emission spectral profiles. However, conventional miniscopes are limited to a single excitation, single focal plane imaging, which does not allow to compensate for chromatic aberration and image from two spectrally distinct calcium indicators.
View Article and Find Full Text PDFFront Neurol
December 2024
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, Hong Kong SAR, China.
Background: Poststroke irritability (PSI) is common among stroke survivors and can lead to a poor quality of life, difficulties in social interactions, criticism from caregivers, and caregiver stress. The planned study will evaluate the clinical, neuropsychological, and magnetic resonance imaging (MRI) correlates of PSI in a cohort of stroke survivors. In addition, the study will examine the 15-month progression of PSI.
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