Purpose: To report a patient with a history of exposure keratopathy who presented with bilateral bacterial keratitis associated with streptococcal pharyngitis and use of bilevel positive airway pressure (BiPAP).
Design: Case report.
Methods: Pulsed-field gel electrophoresis of patient isolates from ocular and pharyngeal cultures.
Results: Ocular and oropharyngeal cultures from a 24-month-old child with a history of cerebral palsy on BiPAP at night revealed the same strain of Streptococcus pyogenes.
Conclusions: Use of mechanical ventilation, such as BiPAP, may precipitate inoculation of eye with respiratory or oropharyngeal pathogens. To the authors' knowledge this is the first report demonstrating the association between concurrent streptococcal pharygitis, keratitis, and use of BiPAP.
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http://dx.doi.org/10.3109/09273948.2011.649152 | DOI Listing |
Microorganisms
November 2024
Microbiology Department, Hospital Universitario 12 de Octubre, Avda. Córdoba s/n, 28041 Madrid, Spain.
The SARS-CoV-2 pandemic significantly affected the epidemiology of , a pathogen associated with various clinical presentations such as pharyngitis, scarlet fever, and invasive diseases. This study analyzed the incidence and characteristics of infections between 2018 and 2023, examining 915 cases categorized as either respiratory or non-respiratory. Respiratory infections predominantly affected children, accounting for 76% of cases, with a median age of 5 [3, 8] years, while non-respiratory infections were more common in adults, with a median age of 46.
View Article and Find Full Text PDFLife (Basel)
December 2024
Physiopathology Department, George Emil Palade University of Medicine, Pharmacy, Sciences and Technology, 540142 Targu Mures, Romania.
Background: This systematic review aimed to synthesize the existing evidence on the use of () probiotics as prophylactic or therapeutic tools for pediatric oral, dental, and respiratory diseases.
Methods: A comprehensive search was carried out across multiple databases using the following terms: , probiotic, children, pediatric.
Results: The systematic literature search identified 613 publications, which were meticulously screened, and, ultimately, 15 suitable citations were included in this systematic review.
Am J Respir Cell Mol Biol
January 2025
Rostock University Medical Center, Institute of Medical Microbiology, Virology and Hygiene, Rostock, Germany.
(Group A Streptococcus, GAS) is a human pathogen that causes local and systemic infections of the skin and mucous membranes. However, GAS is also found asymptomatically in the nasopharynx of infants. GAS infections, including pharyngitis and invasive pneumosepsis, pose significant public health concerns.
View Article and Find Full Text PDFJ Pediatric Infect Dis Soc
December 2024
University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, CSC Room H4 554, Madison, WI.
Expert Rev Mol Diagn
December 2024
Scientific Affairs, Cepheid, Sunnyvale, CA, USA.
Introduction: Rapid and accurate detection of group A (GAS) pharyngitis allows for timely initiation of appropriate antibiotic treatment. This is important to prevent empiric antibiotic overuse while simultaneously lowering the risk of post-infection sequelae. Timely treatment may also reduce forward transmission, which could prevent cases of devastating invasive infections.
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