Amphiphilic block copolymer nanoparticles are conjugated with uropathogenic Escherichia coli type 1 pilus adhesin FimH(A) through amidation chemistry to enable bladder epithelial cell binding and internalization of the nanoparticles in vitro.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325780PMC
http://dx.doi.org/10.1021/ja2091917DOI Listing

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