Objective: To evaluate the cause, frequency and determinants of tremors at secondary care settings.
Methods: A hospital based cross-sectional study for seven years (2002-2009) was carried out at Sindh Govt. Hospital (SGH) Liaqatabad No.10, Karachi. Sample size was 403 and sampling technique was Convenience sampling. A data collection form was designed and all essential variables were recorded regarding age, gender, residence, complaints and their duration, education status, profession, co-morbid and investigations performed. The results were analyzed using SPSS 16.0.
Results: Out of 403 patients 247 (61.5%) were males and 156 (38.5 %) were females. The mean age of the patients was 55.9 +/- 14.2 years. The male to female ratio was 2: 1.6. Enhanced physiological tremor was the most frequent diagnosis. Among whom, females of 40-60 years were mostly affected. Essential tremors were mainly coarse in amplitude, whereas commonest fine tremors were diagnosed as Enhanced Physiological tremor.
Conclusion: Evaluation of patients with tremors showed males to be more affected with essential tremors being the commonest encountered. Orthostatic tremor was rare. Essential tremors were diagnosed by exclusion.
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January 2025
Department of Neurology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA; Initiative for Columbia Ataxia and Tremor, Columbia University, New York, NY 10032, USA. Electronic address:
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Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
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Department of Human Genetics, McGill University, Montréal, Québec, Canada.
Essential Tremor (ET) is the most common movement disorder and has a worldwide prevalence of 1%, including 5% of the population over 65 years old. It is characterized by an active, postural or kinetic tremor, primarily affecting the upper limbs, and is diagnosed based on clinical characteristics. The pathological mechanisms of ET, however, are mostly unknown.
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Department of Neurology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
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