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The prophylactic use of antibiotics in cell culture. | LitMetric

The prophylactic use of antibiotics in cell culture.

Cytotechnology

Tierforschungsanlage, Universität Konstanz, 78343, Konstanz, Germany.

Published: June 1995

This article describes the historical development of the prophylactic use of antibiotics in cell culture as well as their effects on cells. The influence of antibiotics on cell morphology, cellular degeneration and cell death and cellular function is summarized. Cellular DNA as well as protein synthesis are affected which can lead to interference with, or even changes in, metabolic processes. Such effects must be considered in cell culture research. As antibiotics are used in multifold ways, the otherwise standardized conditions in cell culture are no longer comparable. The prophylactic use of antibiotics is rejected for scientific reasons.

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Source
http://dx.doi.org/10.1007/BF00749764DOI Listing

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