Analysis of data from the American Life Panel shows that in the presidential election of 2008 and in multiple statewide elections in 2010, citizens exhibited large differences in their expectations of election outcomes. Expectations were strongly positively associated with candidate preferences, persons tending to believe that their preferred candidate is more likely to win the election. Committed supporters of opposing candidates regularly differed by 20-30% in their assessments of the likelihood that each candidate would win. These findings contribute evidence on the false consensus effect, the empirical regularity that own preferences tend to be positively associated with perceptions of social preferences. We used unique measures of preferences and perceptions that enabled respondents to express uncertainty flexibly. We studied a setting that would a priori seem inhospitable to false consensus--one where persons have little private information on social preferences but substantial common knowledge provided by media reports of election polls.
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http://dx.doi.org/10.1073/pnas.1200861109 | DOI Listing |
Research (Wash D C)
January 2025
College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang 310058, China.
Na1.7 is considered a promising target for developing next-generation analgesic drugs, given its critical role in human pain pathologies. Although most reported inhibitors with strong in vitro activity and high selectivity share the aryl sulfonamide scaffold, they failed to demonstrate marked clinical efficacy.
View Article and Find Full Text PDFIr J Med Sci
January 2025
Department of Clinical Pharmacy, College of Pharmacy, King Khalid University, Abha, Saudi Arabia.
Aim: This study aimed to identify the most commonly used tools by recent pharmacy graduates who successfully passed the Saudi Pharmacists Licensure Examination (SPLE). It also sought to evaluate which tools were perceived as the most useful and representative of the exam content, while considering their monetary value and offering recommendations for future candidates.
Methods: A cross-sectional design was used, involving licensed pharmacists who graduated in 2019 or later and had successfully passed the SPLE.
J Am Podiatr Med Assoc
January 2025
§Northwell Heath, New York, NY.
This objective of this communication is to provide an update from the Council of Teaching Hospitals (COTH) and the American Association of Colleges of Podiatric Medicine (AACPM) with respect to the profession's residency interview process, otherwise known as the Centralized Residency Interview Process (CRIP). During the 2022-2023 academic year, CRIP returned to an in-person format following a period of virtual interviews during the COVID-19 pandemic. Survey data since this change indicate that a large majority of residency program directors and student applicants prefer an in-person format to the residency interview process.
View Article and Find Full Text PDFJ Dent Sci
January 2025
Department of Periodontology and Endodontology, Tohoku University Graduate School of Dentistry, Sendai, Japan.
Background/purpose: Peroxisome proliferator-activated receptor γ (PPARγ) is a major transcription factor of energy metabolism-associated genes, and three PPARγ isoforms have been identified in periodontal tissues and cells. When energy metabolism homeostasis is affected by PPARγ downregulation in periodontal ligament fibroblasts (PDLFs), osteo/cementogenic abilities are markedly lost. Herein, we investigated whether PPARγ agonists promote periodontal tissue regeneration, and which PPARγ isoforms and metabolic pathways are indispensable for osteo/cementogenic abilities.
View Article and Find Full Text PDFClinicoecon Outcomes Res
January 2025
Department of Orthopaedic Surgery, UC San Francisco, San Francisco, CA, 94143-0728, USA.
Background/context: Chronic low back pain (CLBP) is a significant US healthcare burden with millions of lumbar spine procedures annually. Diagnostic tests are essential to guide treatment but provocative discography (PD), the most common diagnostic procedure, is without robust evidence of its value. A non-invasive alternative using Magnetic Resonance Spectroscopy (MRS) offers a potential solution.
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