Objective: The aim of this study was to disclose possible inner ear abnormalities/pathologies by means of high-resolution computed tomography (HRCT) of the temporal bone (TBHRCT) in children with unilateral hearing loss (UHL).
Methods: Retrospective review of audiological evaluation and TBHRCT in 22 children with UHL.
Results: Two thirds of the children showed profound hearing loss. Review of HRCT scans identified inner ear malformations/pathologies in 9 (41%) cases and a high jugular bulb (HJB), always dehiscent with the vestibular aqueduct, in another 5 (22%). Inner ear malformations included enlarged vestibular aqueduct, common cavity and cochleovestibular hypoplasia, while labyrinthine ossification was the detected pathology. In 1 child, the common cavity of the right ear was associated with congenital melanocytic naevus of the left eyelid and lipomeningocele. To the best of our knowledge, this condition has never been described.
Conclusions: The aetiology of UHL may be revealed in more than half of patients by means of TBHRCT. Besides common inner ear abnormalities, TBHRCT should be evaluated carefully to rule out HJB, dehiscences, diverticulum or erosion of inner ear structures.
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http://dx.doi.org/10.1159/000335586 | DOI Listing |
Otol Neurotol
January 2025
Department of Otorhinolaryngology, Head and Neck Surgery, Inselspital, University Hospital Bern and University of Bern, Bern, Switzerland.
Objective: We aimed to investigate the effect of adding "rapid decelerations" and "vibrations" during a SemontPLUS maneuver on the dynamics of the inner ear and the success rate of canalolithiasis repositioning.
Methods: We used a previously described upscaled (5×) in vitro model of the posterior semicircular canal of the inner ear to analyze the trajectory of a single and clumped surrogate otolith particle (metallic sphere) during a SemontPLUS maneuver (-60 degrees below earth horizontal) on a repositioning chair (TRV). We compared the angular displacement of these particles with and without the application of "vibrations" or "rapid decelerations" using TRV.
Environ Sci Technol
January 2025
State Key Joint Laboratory of Environmental Simulation and Pollution Control, College of Environmental Sciences and Engineering, Peking University, Beijing 100871, China.
The effects of particulate matter (PMs) from different cities on the nervous system remain unclear. In this study, aqueous solutions of 0.45 μm membrane-filtered PM from 31 major Chinese cities were intravenously administered to rats.
View Article and Find Full Text PDFJ Comput Assist Tomogr
January 2025
Department of Diagnostic Radiology and Nuclear Medicine, Rush University Medical Center, Chicago, IL.
Treacher Collins syndrome (TCS) is an uncommon congenital disorder predominantly involving craniofacial, orbital, and otological structures. The various ear malformations seen in 9 patients with TCS are described. TCS predominantly affects the external and middle ear structures, with inner ear structures being relatively spared, not unexpected given the dual embryological origin of the human ear.
View Article and Find Full Text PDFHear Res
January 2025
CHU Lille, Department of Otology and Neurotology, F-59000 Lille, France; Univ. Lille, France; Univ. Lille, Inserm, CHU Lille, U1008, F-59000 Lille, France.
Objective: The aim of this study is to detail and evaluate the surgical procedure for perilymph sampling from the cochlear apex in the Mongolian gerbil.
Design: Perilymph sampling from the cochlear apex was performed one to three time in 12 male gerbils aged 8 to 12 months via the submandibular route. 11 of them were previously implanted with intracochlear implants loaded with dexamethasone and placed in the scala tympani, the 12th was used to collect control samples.
J Acoust Soc Am
January 2025
Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland.
The otic capsule and surrounding temporal bone exhibit complex 3D motion influenced by frequency and location of the bone conduction stimulus. The resultant correlation with the intracochlear pressure is not sufficiently understood, thus is the focus of this study, both experimentally and numerically. Experiments were conducted on six temporal bones from three cadaver heads, with BC hearing aid stimulation applied at the mastoid and classical BAHA locations across 0.
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