Highly sensitive DNA hybridization detection with single nanoparticle flash-lamp darkfield microscopy.

Analyst

State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, P. R. China.

Published: July 2012

We developed a novel method for counting single gold nanoparticles in free solution with flash-lamp darkfield microscopy and demonstrated that it could be applied to highly sensitive DNA hybridization detection based on target DNA induced AuNP aggregation and counts reduction.

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Source
http://dx.doi.org/10.1039/c2an16171kDOI Listing

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